Community Research and Development Information Service - CORDIS

Periodic Report Summary 1 - CHILD TRAUMA IN LMIC (RANDOMIZED EVIDENCE OF PSYCHOSOCIAL INTERVENTIONS IN CHILDREN EXPOSED TO TRAUMATIC EVENTS IN LOW AND MIDDLE INCOME COUNTRIES)

Project objectives: The objective of the present study is to carry out an individual patient data meta-analysis using data from all available randomized controlled trials (either published or unpublished) comparing psychosocial intervention with waiting list or no intervention arms in children exposed to traumatic events living in low- and middle-income countries. A comprehensive analysis has the objective of understanding why some children benefit from different interventions more than others.
Work performed since the beginning of the project and main results achieved so far:
1) Systematic review of randomized trials (published and unpublished) evaluating preventive psychosocial interventions in children exposed to traumatic events in humanitarian settings in low- and middle-income countries. Each step of the systematic review was performed according to the Cochrane methodology: search strategy, records screening, identification of eligible studies/excluded studies with reasons/awaiting assessment studies, data extraction form preparation, data extraction and double check, database preparation.
2) Development of an international network of researchers: all authors of included studies were contacted and asked to be part of the individual participant data meta-analysis team. All of them agreed to take part in the project and shared individual participant datasets.
3) Development of a dataset with individual participant data from each included study. Data quality check. Application of the Item Response Theory approach for items harmonization.
4) Risk of bias assessment for each included study according with the Cochrane Risk of Bias tool, using the software Review Manager (version 5.3).
5) Statistical analyses plan and preliminary analyses.
Expected final results and their potential impact and use: As planned in the Working Plan and in the published protocol, we expect to produce meta-analyses of the impact of psychosocial interventions on: post-traumatic stress disorder, depression, anxiety, coping, social support, functioning, and hope. Moreover, we will understand how these interventions work by doing mediators and moderators analyses, and considering the role of specific variables in influencing interventions effects. Such knowledge will facilitate a better matching of intervention with individual and contextual factors in this field, with enormous impact on clinical practice and policies (considering also socio-economic factors).

Contact

Susanna Montalto, (Administrative officer)
Tel.: +39 0 45 8027607
Fax: +39 0 45 8027679
E-mail

Subjects

Life Sciences
Record Number: 196665 / Last updated on: 2017-04-12
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