Community Research and Development Information Service - CORDIS

ERC

REBOOT Report Summary

Project ID: 617280
Funded under: FP7-IDEAS-ERC
Country: Sweden

Periodic Report Summary 2 - REBOOT (Releasing the brakes on adult plasticity)

Age-related cognitive impairments compromise the functional capacity of aging individuals, and create major individual and societal costs. Developing means for preserving and restoring cognitive functioning in old age is therefore of great importance. Cognitive training is one promising route, but results have been disappointing. The main objectives of this project are to discover feasible ways to transiently increase brain plasticity in older humans and to uncover the neural mediators of training-related change in performance, so that the effects of cognitive training can be increased and better understood. To achieve these goals, four studies combining cognitive training with either pharmacology, brain stimulation, or physical exercise were proposed. The results from the first study show that the brain stimulation (transcranial-direct current) did not improve cognitive performance or the outcomes of cognitive training. Our results demand a more cautious appraisal of the potential applications of current stimulation. Ongoing and future work in this project focus on pharmacological means and physical exercise as routes to increase brain plasticity in older age.

Reported by

KAROLINSKA INSTITUTET
Sweden
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