Community Research and Development Information Service - CORDIS

Conceptual design of an automated immunoanalyzer to exploit the benefits of the capillary device

To exploit the benefits in terms of assay speed, reagent volumes, simplified sample handling and elimination of pipetting, a capillary immunoanalyzer has been in principle designed. It consists of 4 compartments, including capillary storage, capillary transfer, sample management and detection compartments. A belt based transfer system moves the capillaries across the various compartments with the help of a stepping motor. Automatic valves connect to the capillary ends, for sample reagent and washing solutions aspiration and dispensing using motorized dispensing syringes. Owing to the multi-analyte nature of the capillaries and their small volume, the immunoanalyzer can have the footprint of a A4 paper and could be ideal for clinical uses where the speed increase and the cost reduction of the assays are critical factors for improved public health care management.

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