Community Research and Development Information Service - CORDIS

Development of fish PPAR antibodies

An antibody specific for the marine fish PPAR gamma has been developed through the use of synthetic peptides corresponding to a highly conserved region within the A/B domain of the marine fish receptors This antibody has been tested with various success on bacterially expressed receptor, on in vitro translated receptor, and on fish tissue protein extracts.

Improving the efficiency of this antibody could result in an important tool for the study of marine fish PPARs, through immunocytochemical, imunohistological, and ELISA applications. Improved efficiency could result in the commercial exploitation of this antibody. Furthermore, the development process (peptide sequence etc.) has the potential to be patented.

Reported by

Universidad Complutense de Madrid
Universidad Complutense de Madrid, Facultad de Veterinaria, Departemento de Bioquimica y Biol. Mol. IV, Ciudada Universitaria
28040 Madrid
Spain
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