Servizio Comunitario di Informazione in materia di Ricerca e Sviluppo - CORDIS

Study of the immunotoxicity of EBDTC and mixed pesticide exposure in agricultural (potato) workers in Finland

An epidemiological study of the immunotoxicity of EBDTC and mixed pesticide exposure in agricultural (potato) workers was performed in Finland. Exposure parameters and immune parameters were measured, and questionnaires were applied to the workers. A deterministic model based on the information of questionnaires was developed for the exposure assessment of workers during the exposure period. The model is used with biomonitoring data in order to divide workers into homogenous exposure groups. The model also gives an estimate of exposure level if the biomonitoring result of the worker is not available. Also the EUROPOEM and German models were tested with the exposure data. The results of the study indicate significant suppression of T lymphocytes and inflammatory parameters in exposed workers compared to controls.

Reported by

Department of Pharmacology and Toxicology, University of Kuopio
POB 1627
70211 Kuopio
Finland
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