Servicio de Información Comunitario sobre Investigación y Desarrollo - CORDIS

The new inhibitors have been tested for inhibitory efficacy in yeast and osteoclasts. Assays for the effects in osteoclasts were developed as part of the project

A range of chemcial compounds have been synthesised which are able to inhibit the enzyme complex. Some represent quite new approaches to interfering with the mechanism of action of the enzyme. These compounds may have value as leads in the development of therapeutic approaches to osteoporosis and cancer.

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UNIVERSITY OF LEEDS
Woodhouse Lane
LEEDS
United Kingdom
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