Community Research and Development Information Service - CORDIS

Role of GDNF ligands and receptors in lesion-induced neurogenesis

GDNF was delivered using intra-striatal infusion for one week after stroke. Animals were then given the mitosis marker BrdU and we analyzed cell proliferation in the subventricular zone. The GDNF infusion caused a significant (33%) increase of cell proliferation in the ipsilateral subventricular zone as compared to vehicle-injected animals.

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Sten WENNERSTROM
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