Forschungs- & Entwicklungsinformationsdienst der Gemeinschaft - CORDIS

Generation of vectors that drive efficient expression of wild-type and mutant PABPN1 cDNA

We produced novel genetic vectors for PABPN1 expression based on ubiquitous chromatin opening elements.

The new vectors for PABPN1 expression contain promotors that are able to overcome variegated expression and silencing that is commonly induced after transgene integration into the host cell genome.


Michael ANTONIOU, (Principal Scientist)
Tel.: +44-2071883708
Fax: +44-2071882585
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