Service Communautaire d'Information sur la Recherche et le Développement - CORDIS

FP5

TRI-EX Résumé de rapport

Project ID: QLG2-CT-2001-01673
Financé au titre de: FP5-LIFE QUALITY
Pays: United Kingdom

Generation of vectors that drive efficient expression of wild-type and mutant PABPN1 cDNA

We produced novel genetic vectors for PABPN1 expression based on ubiquitous chromatin opening elements.

The new vectors for PABPN1 expression contain promotors that are able to overcome variegated expression and silencing that is commonly induced after transgene integration into the host cell genome.

Reported by

KING'S COLLEGE LONDON
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SE1 9RT LONDON
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