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Attempts at quantifying redox-active iron

Not all of the non-transferrin-bound iron is redox-active. We attempted to measure the redox-active fraction of NTBI in serum samples provided by Prof. J. Marx by reducing iron(III) by ascorbate, a physiological reductant, and trapping the iron(II) with ferrozine. We found that about 1/3 of NTBI is redox-active, in general agreement with the literature. More studies are needed for a publication.

Contact

Willem H. KOPPENOL, (Professor)
Tel.: +41-44-6322875
Fax: +41-44-6321090
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