Servizio Comunitario di Informazione in materia di Ricerca e Sviluppo - CORDIS


IMPALED Sintesi della relazione

Project ID: QLK3-CT-2002-01956
Finanziato nell'ambito di: FP5-LIFE QUALITY
Paese: France

Mechanisms of HIV-induced cell death

The subject matter of the present invention relates to an in vitro method for the screening of anti-HIV compounds, or for predicting the progression of HIV related diseases, or for determining the efficiency of an anti-HIV-1 treatment based on the measuring of the expression level of Puma and, optionally, on the measuring of the phosphorylated P53 and/or the p38 MAP kinase protein level in circulating white blood cells of a sample from a HIV infected patient, particularly HIV-1. The invention further comprises a method for the diagnostic of HIV infection in a patient and kits for performing these methods.


Guido KROEMER, (Research Director)
Tel.: +33-1-42116046
Fax: +33-1-42115244