Community Research and Development Information Service - CORDIS


PHYTOS Report Summary

Project ID: QLK1-CT-2000-00431
Funded under: FP5-LIFE QUALITY
Country: Italy

Biological data bank

A randomised, double blind, placebo controlled parallel multi-centre trial was conducted in The Netherlands (TNO Quality of Life, Zeist), Italy (INRAN, Rome) and France (INRA, Clermont-Ferrant) to investigate the effects of 1-year IF-enriched food/s consumption on bone mineral metabolism, bone density and on hormonal status in early postmenopausal women. 91 subjects completed the study in the Netherlands, 78 in Italy and 68 in France. Subjects were randomly allocated to a treatment group (IF+) and a control group (IF-). The IF+ group were administered a mean daily isoflavone intake of 110mg. Urine, serum and plasma samples are still available. More refined techniques could be used to evaluate biological effects of isoflavones, for example using proteomic and metabonomic techniques.


Giancarlo VIGLIONE
Tel.: +39-06-51494571
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