Community Research and Development Information Service - CORDIS

Biological data bank

A randomised, double blind, placebo controlled parallel multi-centre trial was conducted in The Netherlands (TNO Quality of Life, Zeist), Italy (INRAN, Rome) and France (INRA, Clermont-Ferrant) to investigate the effects of 1-year IF-enriched food/s consumption on bone mineral metabolism, bone density and on hormonal status in early postmenopausal women. 91 subjects completed the study in the Netherlands, 78 in Italy and 68 in France. Subjects were randomly allocated to a treatment group (IF+) and a control group (IF-). The IF+ group were administered a mean daily isoflavone intake of 110mg. Urine, serum and plasma samples are still available. More refined techniques could be used to evaluate biological effects of isoflavones, for example using proteomic and metabonomic techniques.

Reported by

NATIONAL INSTITUTE OF RESEARCH FOR FOOD AND NUTRITION
546,Via Ardeatina
00178 Roma
Italy
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