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FP5

ASIARESIST Résumé de rapport

Project ID: ICA4-CT-2001-10028
Financé au titre de: FP5-INCO 2
Pays: Thailand

Antimicrobial multi resistance in heterophic bacteria originated from Southeast Asian aquaculture origin

The information on MIC from SEA partners showed that the heterotrophic bacterial population in aquaculture sources comprised was both susceptible and resistant to CHL. Overall; the three country sub collections of CHL-resistant bacteria were similar.

The majority of CHL-resistant isolates (82.6%) showed a MIC =>512 ppm. They also exhibited multi-resistance to CHL and ampicillin (AM), tetracycline (TE), nitrofurantoin (F/M) and trimethoprim/sulfamethoxazole (SXT) at various frequencies, but were relatively susceptible to norfloxacin (only 28% being resistant to this antibiotic). The most common profiles were of resistance to 3 and 4 antibiotics (14% and 15% of tested isolates, respectively), the commonest resistance profiles being CHL-AM-TE-SXT and CHL-AM-TE-SXT-F/M.

Resistance to CHL alone was rare (3%). (Annex VI) Moreover, there was a tendency for CHL-resistant isolates with higher MIC values to be resistant to greater numbers of antibiotics than those with lower MICs. Similarly, bacterial isolates from integrated farms showed resistance to more antibiotics than those obtained from monoculture farms (99% confidence interval).

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Supranee CHINABUT, (Senior Advisor on Fish Diseases)
Tél.: +66-2-5796803
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