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Synthesis of the glucosyl acceptor, precursor of GlcA units

The title compound was synthesized in six steps starting from commercial pentaacetylglucose. The procedure can be made on large scale (100 grams) and requires only a purification step. The obtained compound is a flexible intermediate, which can be used to prepare heparin-like oligosaccharides containing glucuronic acid or glucose moieties.


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