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  • Synthesis of methyl 2-azido-3-O-benzyl-2-deoxy-6-O-levulinoyl-alfa-D-glucopyranoside, the reducing end of pentasaccharides designed as potential substrates of heparanase enzyme
FP5

HEPARANASE Report Summary

Project ID: QLK3-CT-2002-02049
Funded under: FP5-LIFE QUALITY
Country: Italy

Synthesis of methyl 2-azido-3-O-benzyl-2-deoxy-6-O-levulinoyl-alfa-D-glucopyranoside, the reducing end of pentasaccharides designed as potential substrates of heparanase enzyme

The title compound was synthesized in 10 steps from commercial D-glucosamine through a (partially) novel chemo-enzymatic procedure. The product here described is a starting material for the preparation of pentasaccharides designed as potential substrates of heparanase enzyme.

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THE UNIVERSITY OF MILANO
Via Venezian 21
20133 MILANO
Italy
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