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FP5

HEPARANASE Résumé de rapport

Project ID: QLK3-CT-2002-02049
Financé au titre de: FP5-LIFE QUALITY
Pays: Italy

Synthesis of GlcN-alfa-(1-4) Glc disaccharide

The title disaccharide was synthesized in 10 overall steps from commercial D-glucosamine and the properly protected allyl beta-D-glucopyranoside. This disaccharide is an intermediate for the synthesis of the non reducing end of the family of pentasaccharides putative substrates and/or inhibitors of the heparanase enzyme.

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Enrico DECLEVA, (CHANCELLOR)
Tél.: +39-025-0314060
Fax: +39-025-0314061
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