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FP5

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Project ID: ICA4-CT-2001-10014
Finanziato nell'ambito di: FP5-INCO 2
Paese: Italy

Development of a conceptual framework to control antimicrobial use and resistance in low-income countries

A conceptual framework was developed to describe antimicrobial use and resistance in healthy children aged 6-72 months from urban and remote rural communities of Bolivia and Peru.

Antimicrobial use was determined by the household survey methodology and antimicrobial resistance in commensal organisms of the gut (Escherichia coli) by using a simple and robust screening method. Selected resistant bacteria were further investigated at phenotype and genotype level. Other factors influencing the phenomenon were considered, including national drug policy, non-human use of antimicrobials and water contamination.

To improve the situation a community intervention package focusing on rational use of antimicrobials was evaluated. It was developed and implemented in collaboration with the local public and private health services on the basis of the generated results enforced by the national drug policy.

The framework aimed to contribute to a more appropriate antimicrobial use and evidence based antimicrobial policy.

Reported by

University of Florence, Division of Infectious Diseases
Viale Morgagni 85
50134 Florence
Italy
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