Wspólnotowy Serwis Informacyjny Badan i Rozwoju - CORDIS

Establishment of a protocol for induction of upper-airway inflammation in mouse (mouse model of allergy)

A mouse model of allergy to Ovalbumin for studying the inflammatory immune response has been established in collaboration with Dr. Sarah Howie (University of Edinburgh).

The protocol we have followed implies 2 intra-peritoneal administrations of alum-precipitated-Ovalbumin at weekly intervals, followed by 3 intra-tracheal (i.t.) injections of soluble Ovalbumin at 4 day intervals and sacrifice of mouse with collection of blood sample/ organs/ BALF at different time points after the last i.t. administration of antigen.

Reported by

Consiglio Nazionale Ricerche
Istituto di Genetica A. Buzzati Traverso, Via P. Castellino, 111
75010 Napoli
Italy
Śledź nas na: RSS Facebook Twitter YouTube Zarządzany przez Urząd Publikacji UE W górę