Servizio Comunitario di Informazione in materia di Ricerca e Sviluppo - CORDIS

Formulation of plasmid pCMV Derp1 and pCMVIC80 Derp1 (containing the gene encoding for the dust mite allergen of Dermatophagoides pteridissinus) with

The formulation of the pCMVDerP1 and pCMVIC80DerP1 plasmids with cationic particles is aimed at increasing the immunogenicity of the corresponding naked plasmid DNA, to be used in murine models of naïve and allergic mice. The formulations are capable of inducing an allergen-specific cellular response in non-allergic mice.

Reported by

Novartis Vaccines and Diagnostics Srl (ex Chiron)
Via Fiorentina, 1
75010 Siena
Italy
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