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FP5

CERBERUS Résumé de rapport

Project ID: QLK5-CT-2002-01027
Financé au titre de: FP5-LIFE QUALITY
Pays: France

Anti-microbial and anti-adhesive effects

There is an increasing need for the introduction of novel bioactive compounds to fight problems of biocide resistance by microbial strains. Large crude extracts and fractions of barks and knots from pulp wastes (pulp and paper industries) have been studied to detect the most effective anti-microbial extracts against micro-organisms and the conditions of their implementation to promote wood extractives as anti-microbial agents (bactericide, bacteriostatic, fungicide and fungistatic), slimicide and dispersing agent.

The anti-microbial and anti-adhesive effects of crude extracts were two of the main expected results foreseen. It is based on an original protocol based on broth micro-dilution in order to screen the anti-microbial activity of crude extracts towards five non-pathogenic bacterial strains, which have been identified. In a first phase, 21 extracts have been tested against microorganisms to conclude that 5 extracts were shown to be the most potent ones: ethanol extracts of knots from Pinus nigra (black pine), Pinus pinaster (maritime pine), Populus deltoids (poplar), Eucalyptus globulus (eucalypt) and Qercus robur (oak). Finally, the most effective anti-microbial extracts or fraction as well as the most effective concentrations were determined for each bacteria.

The most potent extracts were studied for anti-adhesive effect on 3 materials (stainless steel, PTFE and glass). Two samples of hexane and water extracts of barks (Eucalyptus globulus and Pinus pinaster) have demonstrated interesting effect toward bacterial adhesion.

Reported by

CENTRE TECHNIQUE DU PAPIER
DOMAINE UNIVERSITAIRE BP 251
38044 GRENOBLE
France
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