Wspólnotowy Serwis Informacyjny Badan i Rozwoju - CORDIS

Clinical indications

In this result clinical indications in relation with the different pathologies that can take benefit of a minimally invasive visual approach of spinal cord are defined. Four pathological circumstances have been identified: the traumatic lesions of the spinal cord, the malformations, the tumours of spinal cord and the arachnoïd reactions after surgery.

In the first category (traumatic lesions of the spinal cord) the fluidic system of Minosc can be used for the injection of neurotransmitters like all the varieties of NGF(nerve growth factors) or inductors of new vessels to improve the trophicity of the nervous tissue as well as for the pumping of hematomas.

In the second category (malformations), the important perturbation of the CSF circulation in the spina bifida pathology, requires drainage and dissection of cysts and cavities: Minosc indications can be found especially in case of recurrence of troubles and to treat cystic cavities. In the same category, treatment of arterio-venous malformations (AVM) can be also possible using very thin catheter to pump or to close a venous drainage inaccessible by the interventional way.

Regarding tumors, the possibility to do a biopsy using Minosc procedure will be of great help avoiding surgical exploration only for biopsy.

In case of Post surgical arachnoïd reactions, having the possibility to have a look at the local situation and to clean gently with a hydrodissection the fibrous adherences between roots until the level of the vertebral foramen could be of great help and solve the problem of reduced nerve motility.

That is particularly true for the surgical approach done on the cauda equine where all the inferior roots are concentrated. Removing a cyst or a little radicular tumour can be also a possibility for Minosc as well as the liberation of an isolated sector of the meningeal space blocking the free circulation of CSF.

It is important to have the possibility to suggest to patients having had many surgical operations without a full clinical success, to get a non-invasive neuromyeloscopy in order for the patient and the physician in charge to see images of the real local situation.

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University of Montpellier
263 Rue du Caducée
34195 Montpellier
France
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