Community Research and Development Information Service - CORDIS

FP5

CRYOCYTE Report Summary

Project ID: Q5RS-2002-00784
Funded under: FP5-LIFE QUALITY
Country: Spain

Characterization of a ovarian aquaporins

1. A novel subfamily of molecular water channels in teleosts, related to mammalian aquaporin-1(AQP1), named AQP1o, was discovered and characterized. These channels are highly expressed in the ovary of marine fish.
2. The sub-cellular localization of AQP1o in gilthead seabream oocyte was elucidated, demonstrating its role during hydration of the oocyte that occurs during oocyte maturation.
3. Amino acid domains located in the C-termini of gilthead seabream AQP1o involved in the regulation of the trafficking of the proteins into the plasma membrane of the oocyte were identified.
4. Protocols were developed for the induction of ovulation in vitro of gilthead seanream and zebrafish ovarian follicles.

Contact

Joan CERDA, (Head of Unit)
Tel.: +34-93-2309531
Fax: +34-93-2309555
E-mail
Record Number: 44403 / Last updated on: 2007-08-22
Information source: e-TIP
Collaboration sought: Further research or development support
Stage of development: Scientific and/or technical knowledge (basic research)