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Monitoring of oocyte viability after cryopreservation using genomic tools

We have developed an Oocyte Viability Molecular Signature (OVMS) assay for monitoring cryo-preservation and oocyte manipulations. The data obtained demonstrated that the polarization of maternal transcripts inside the oocyte could be used as a new and original method to monitor oocyte viability after manipulation and/or cryo-preservation and will help in cryo-preservation protocol refinement. OVMS assay is therefore a nice complementary approach for the evaluation of oocyte viability both before and after a cryo-preservation procedure, and may substitute visual and staining methods, and to heavier functional evaluations.

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UNIVERISTY OF BORDEAUX
AVENUE DES FACULTES BAT. B2
33405 BORDEAUX
France
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