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Monitoring of oocyte viability after cryopreservation using genomic tools

We have developed an Oocyte Viability Molecular Signature (OVMS) assay for monitoring cryo-preservation and oocyte manipulations. The data obtained demonstrated that the polarization of maternal transcripts inside the oocyte could be used as a new and original method to monitor oocyte viability after manipulation and/or cryo-preservation and will help in cryo-preservation protocol refinement. OVMS assay is therefore a nice complementary approach for the evaluation of oocyte viability both before and after a cryo-preservation procedure, and may substitute visual and staining methods, and to heavier functional evaluations.


Patrick J. BABIN, (Professor)
Tel.: +33-5-40008776
Fax: +33-5-40008915
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