Wspólnotowy Serwis Informacyjny Badan i Rozwoju - CORDIS


BIOSOFT Streszczenie raportu

Project ID: 40078
Źródło dofinansowania: FP6-MOBILITY
Kraj: Italy

Final Activity Report Summary - BIOSOFT (Light scattering investigation of bio-functionalized amphiphiles)

We have measured the Langmuir adsorption of DNA-functionalised surfactants ('amphinucleosides') by means of light scattering from colloidal model particles near the refractive index matching. We highlight the effect of the hydrophobic tails and specific zwitterionic head groups. We have investigated hydrophobic and specific base pairing interactions occurring in double shells on the surface colloidal particles.

In addition we studied the self-assembling of amphinucleosides with polar heads formed by nine DNA bases. We measured the phase diagram as a function of the ionic strength and temperature, showing evidences of a critical point far from room temperature (around 80C). Finally we have determined the corresponding correlation length and we have compared our results with different model surfactants.


Roberto PIAZZA
Tel.: 0039 02 2399 6386
Faks: 0039 02 2399 6309
Adres e-mail
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