Community Research and Development Information Service - CORDIS

Diabetes research gains foothold in India

Type II diabetes affects a significant part of the population not only in the EU but across the globe. Identifying the genetic factors affecting the onset of diabetes is therefore an extremely important task in the effort towards the discovery of novel medications for the condition.
Diabetes research gains foothold in India
A research team from India set out to examine the genetic determinants of type II diabetes in the Indian population thus adding to the knowledge base on diabetes worldwide. Scientists centred on the chromosomal locations that contain the genes involved in diabetes among Indians.

A total of one thousand diabetic sib-pairs participated in the study in order to specifically the genetic loci involved in disease onset. Furthermore, scientists aimed to show whether specific alterations in DNA structure might play a role in pathogenesis.

The results of the study are expected to shed light on the mechanisms of action of specific genes that lead to type II diabetes. In addition, the role of epigenetic factors (DNA alterations like methylation) will be made clearer. Overall new data are expected to assist scientists in pinpointing the exact causes of the disease.

The Indian Institute of Genomics and Integrative Biology is seeking to form collaborations in order to further this line of research.

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Record Number: 82203 / Last updated on: 2005-11-16
Domain: Biology, Medicine