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Targeted discovery of novel cellulases and hemicellulases and their reaction mechanisms for hydrolysis of lignocellulosic biomass
Start date:2008-08-01
End date:2012-07-31
Project Acronym:DISCO
Project status:Completed
Coordinator
| Organization name:TEKNOLOGIAN TUTKIMUSKESKUS VTT | |
| Administrative contact | Address |
|
Name:Riitta |
Vuorimiehentie 3 1000 ESPOO SUOMI/FINLAND Region:MANNER-SUOMI UUSIMAA |
| Tel:+35-820-7225206 | |
| Fax:+35-820-7227071 | |
| E-mail:Contact | |
| URL:http://www.vtt.fi | Organization Type: |
Description
Objective:
The aim of the proposed DISCO project is to develop more efficient and therefore more cost-effective cellulosic and hemicellulosic enzyme tools for the enhanced hydrolysis of pre-treated lignocellulosic biomass in simultaneous saccharification and fermentation (SSF) conditions for bioethanol production. The focus will be on enzymes having increased catalytic activity on various types of relevant European lignocellulosic biomass. In addition enzymes with lower affinity for lignin shall also be developed.
Such enzymes would increase the effective amount of cellulases/ hemicellulases for cellulose hydrolysis. Furthermore the recycling of these enzymes would be applicable. The approach in this proposal is to discover the desired activities by combining classical and modern screening technologies. The enzymes will be produced in suitable host systems for industrial enzyme production. The project also focuses on elucidation of enzymatic hydrolysis mechanisms, about which there is a paucity of knowledge. The project will determine the limiting structural factors in these mechanisms by characterisation of the substrate during the course of the hydrolysis and the remaining recalcitrant residue.
Achievements:
General information:
Project Details
Start date:2008-08-01
End date:2012-07-31
Duration:48 months
Project Reference:211863
Project cost:4001460 EURO
Project Funding:2985845 EURO
Programme Acronym:
FP7-KBBE
Programme type:Seventh Framework Programme
Subprogramme Area:LIGNOCELLULOSIC ENZYMES - Development of cellulases for lignocellulosic biomass pre-treatment
Contract type:Small or medium-scale focused research project
URL:
Subject index:Biotechnology
Other Indexes:screening,enzymes,biomass,biorefinery,mechanisms,cellulase,hemicellulase,lignocellulose,hydrolysis,discovery,bioethanol
Results for this Project
| Periodic Report Summary - DISCO (Targeted discovery of novel cellulases and hemicellulases and their reaction mechanisms for hydrolysis of lignocellulosic biomass) | 18/01/2013 |
Other participants
| Organization name:INSTITUTE OF FOOD RESEARCH | |
| Administrative contact | Address |
|
Name:Mary |
Norwich Research Park, Colney NORWICH UNITED KINGDOM Region:EAST ANGLIA Norfolk |
| Tel:+44-1603450244 | |
| Fax:+44-1603450887 | |
| E-mail:Contact | |
| URL: | Organization Type:Research,Other |
| Organization name:A.N. BAKH INSTITUTE OF BIOCHEMISTRY OF THE RUSSIAN ACADEMY OF SCIENCES | |
| Administrative contact | Address |
|
Name:Vladimir |
Leninsky Prospect 33 MOSCOW Russian Federation Region: |
| Tel:+7-4959523441 | |
| Fax:+7-4959523441 | |
| E-mail:Contact | |
| URL:http://www.inbi.ras.ru | Organization Type: |
| Organization name:WAGENINGEN UNIVERSITEIT | |
| Administrative contact | Address |
|
Name:Jos |
Costerweg 50 9101 WAGENINGEN NEDERLAND Region:NOORD-NEDERLAND FRIESLAND Noord-Friesland |
| Tel:+31-317485313 | |
| Fax:+31-317484132 | |
| E-mail:Contact | |
| URL:http://www.wageningenuniversiteit.nl/uk/ | Organization Type:Education |
| Organization name:HELSINGIN YLIOPISTO | |
| Administrative contact | Address |
|
Name:Sanna-Maija |
Yliopistonkatu 4 HELSINKI SUOMI/FINLAND Region:MANNER-SUOMI UUSIMAA |
| Tel:+35-891-9159792 | |
| Fax:+35-891-9158873 | |
| E-mail:Contact | |
| URL:http://www.helsinki.fi/bioscience/ | Organization Type:Education |
| Organization name:BUDAPESTI MUSZAKI ES GAZDASAGTUDOMANYI EGYETEM | |
| Administrative contact | Address |
|
Name:Miklós |
MUEGYETEM RAKPART 3 1521 PF 91 BUDAPEST MAGYARORSZAG Region:KOZEP-MAGYARORSZAG Budapest |
| Tel:+36-14632277 | |
| Fax:+36-14632270 | |
| E-mail:Contact | |
| URL:http://www.bme.hu | Organization Type:Education |
| Organization name:COOPERATIE CEHAVE LANDBOUWBELANG U.A. | |
| Administrative contact | Address |
|
Name:Albert Jan |
Poort van Veghel 4949 VEGHEL NEDERLAND Region:ZUID-NEDERLAND NOORD-BRABANT Midden-Noord-Brabant |
| Tel:+31-413382255 | |
| Fax:+31-413382013 | |
| E-mail:Contact | |
| URL:http://www.chv-lbb.nl | Organization Type: |
| Organization name:BIOGOLD OU | |
| Administrative contact | Address |
|
Name:Priit |
Lossi TALLINN EESTI Region:EESTI Eesti Põhja-Eesti |
| Tel:+372-5013653 | |
| Fax:+372-6775288 | |
| E-mail:Contact | |
| URL:http://www.biogold.ee | Organization Type: |
| Organization name:DYADIC NEDERLAND BV | |
| Administrative contact | Address |
|
Name:Wim |
NIEUWE KANAAL 7 S WAGENINGEN NEDERLAND Region:OOST-NEDERLAND GELDERLAND Arnhem/Nijmegen |
| Tel:+31-317465458 | |
| Fax:+31-317465455 | |
| E-mail:Contact | |
| URL: | Organization Type: |
| Organization name:SEKAB E-TECHNOLOGY | |
| Administrative contact | Address |
|
Name:Torbjörn |
Hoerneborgsvaegen OERNSKOELDSVIK SVERIGE Region: |
| Tel:+46-66075167 | |
| Fax:+46-66054903 | |
| E-mail:Contact | |
| URL:http://www.sekab.com | Organization Type: |
| Organization name:G R WRIGHT AND SONS LTD | |
| Administrative contact | Address |
|
Name:Lesley |
Ponders End Mills ENFIELD UNITED KINGDOM Region:SOUTH EAST (UK) GREATER LONDON |
| Tel:+44-02083446900 | |
| Fax:+44-02088040533 | |
| E-mail:Contact | |
| URL:http://www.wrightsflour.co.uk | Organization Type: |
| Organization name:AGRIFIRM GROUP BV | |
| Administrative contact | Address |
|
Name:Erik |
BOOGSCHUTTERSTRAAT 1A 2000 APELDOORN NEDERLAND Region:WEST-NEDERLAND NOORD-HOLLAND Agglomeratie Haarlem |
| Tel:+31-413382255 | |
| Fax:+31-413382013 | |
| E-mail:Contact | |
| URL:http://www.agrifirm.com | Organization Type: |
Record control number:88398
