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From Biodiversity to Chemodiversity: Novel Plant Produced Compounds with Agrochemical and Cosmetic interest
Start date:2010-04-01
End date:2014-03-31
Project Acronym:AGROCOS
Project status:Execution
Coordinator
| Organization name:NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS | |
| Administrative contact | Address |
|
Name:Efi |
CHRISTOU LADA 6 ATHENS HELLAS Region:ATTIKI |
| Tel:+30-2103689096 | |
| Fax:+30-2103689008 | |
| E-mail:Contact | |
| URL:http://www.elke.uoa.gr | Organization Type: |
Description
Objective:
The consortium will discover and carry to the stage of development candidates, plant derived small molecules with potential as new cosmetic and agrochemical agents. These compounds will derive from plants originating from major biodiversity hotspots in Europe, Africa, Latin America, and the Asia-Pacific region.
The starting point of the project will be a diversity-oriented natural product library of 500 compounds from the existing compound repositories of three project partners. Screening of this compound library in assay panels for agrochemical (antifungal, herbicidal, insecticidal) and cosmetic properties (UV-protection, anti-aging, anti-hyper-pigmentation) will rapidly identify promising scaffolds. This knowledge will serve as entry points for a chemotaxonomy and chemo-diversity oriented collection of plants which are thought to contain structural variants and decorations of these scaffolds. A liquid library of 3600 extracts will be generated and screened. Stringent prioritization and profiling procedures will generate 300 compounds as focused sub-libraries around the privileged scaffolds.
A state-of-the-art technology platform for miniaturized natural product discovery will be used for the purpose. Evaluation of these sub-libraries will lead to 30 compounds which will undergo advanced testing to qualify 5 compounds as development candidates for novel agrochemical and/or cosmetic agents with new or improved properties over existing active ingredients. An additional outcome of the project will be an extract library with a unprecedented level of associated spectroscopic information and metadata, to be used for future purposes. The high-caliber consortium brings together international leaders in small molecule natural products, bio-prospection, leading industries in agro-chemistry, cosmetics, and spectroscopic data management and analysis.
Achievements:
General information:
Project Details
Start date:2010-04-01
End date:2014-03-31
Duration:48 months
Project Reference:245336
Project cost:4274788 EURO
Project Funding:2903633 EURO
Programme Acronym:
FP7-KBBE
Programme type:Seventh Framework Programme
Subprogramme Area:Prospecting for novel plant-produced compounds
Contract type:Small or medium-scale focused research project
URL:
Subject index:Agricultural biotechnology , Biotechnology
Results for this Project
| Periodic Report Summary - AGROCOS (From Biodiversity to Chemodiversity: Novel Plant Produced Compounds with Agrochemical and Cosmetic interest) | 23/07/2012 |
Other participants
| Organization name:NATIONAL CENTER FOR SCIENTIFIC RESEARCH "DEMOKRITOS" | |
| Administrative contact | Address |
|
Name:Marina |
Patriarchou Gregoriou Str. P.O. Box 60228 AGHIA PARASKEVI HELLAS Region: |
| Tel:+30-210-6503096 | |
| Fax:+30-210-6523139 | |
| E-mail:Contact | |
| URL:http://www.demokritos.gr | Organization Type:Research |
| Organization name:BASF SE | |
| Administrative contact | Address |
|
Name:Michael |
CARL BOSCH STRASSE 38 LUDWIGSHAFEN DEUTSCHLAND Region:RHEINLAND-PFALZ RHEINHESSEN-PFALZ Ludwigshafen am Rhein, Kreisfreie Stadt |
| Tel:+49-6216055243 | |
| Fax:+49-6216078502 | |
| E-mail:Contact | |
| URL:http://www.basf.com | Organization Type: |
| Organization name:COUNCIL FOR SCIENTIFIC AND INDUSTRIAL RESEARCH | |
| Administrative contact | Address |
|
Name:Sandy |
Meiring Naude Road, Brummeria 46 395 PRETORIA SOUTH AFRICA Region: |
| Tel:+27-116502210 | |
| Fax:+27-116502256 | |
| E-mail:Contact | |
| URL:http://www.csir.co.za | Organization Type: |
| Organization name:BRUKER BIOSPIN GMBH | |
| Administrative contact | Address |
|
Name:Eberhard |
Am Silberstreifen RHEINSTETTEN DEUTSCHLAND Region:BADEN-WÜRTTEMBERG KARLSRUHE Karlsruhe, Landkreis |
| Tel:+49-72151616420 | |
| Fax:+49-721516191420 | |
| E-mail:Contact | |
| URL:http://www.bruker-biospin.de | Organization Type: |
| Organization name:CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE | |
| Administrative contact | Address |
|
Name:Michèle |
Rue Michel -Ange 3 PARIS FRANCE Region:ÎLE DE FRANCE Ile de France Paris |
| Tel:+33-69823264 | |
| Fax:+33-69823210 | |
| E-mail:Contact | |
| URL:http://www.cnrs.fr | Organization Type: |
| Organization name:UNIVERSITAET BASEL | |
| Administrative contact | Address |
|
Name:Matthias |
Petersplatz 1 BASEL SCHWEIZ/SUISSE/SVIZZERA Region:NORDWESTSCHWEIZ Basel-Stadt |
| Tel:+41-61-2671425 | |
| Fax:+41-61-2671474 | |
| E-mail:Contact | |
| URL:http://www.unibas.ch | Organization Type:Education |
| Organization name:UNIVERSIDAD DE PANAMA | |
| Administrative contact | Address |
|
Name:Betty Ann |
CALLE MANUEL ESPINOSA BATISTA SN PANAMA PANAMA Region: |
| Tel:+507-5232150 | |
| Fax:+507-5232150 | |
| E-mail:Contact | |
| URL:http://www.up.ac.pa | Organization Type: |
| Organization name:KORRES S.A. NATURAL PRODUCTS (KORRES ANONIMI ETERIA FYSIKA PROIONTA) | |
| Administrative contact | Address |
|
Name:Panagiotis |
57th Km ATHENS-LAMIA NATIONAL ROAD INOFYTA HELLAS Region: |
| Tel:+30-2262054548 | |
| Fax:+30-2262054545 | |
| E-mail:Contact | |
| URL: | Organization Type: |
Record control number:94701
