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health-economic modelling of PREvention strategies for Hpv-related Diseases in European CounTries
Start date:2010-05-01
End date:2013-04-30
Project Acronym:PREHDICT
Project status:Completed
Coordinator
| Organization name:VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG | |
| Administrative contact | Address |
|
Name:Johannes |
De Boelelaan 1105 AMSTERDAM NEDERLAND Region:WEST-NEDERLAND NOORD-HOLLAND Groot-Amsterdam |
| Tel:+31-20-4444909 | |
| Fax:+31-20-4444475 | |
| E-mail:Contact | |
| URL:http://www.vu.nl | Organization Type: |
Description
Objective:
The goals of the PREHDICT study are to determine prerequisites and strategies for vaccination in European countries and to predict the impact of vaccination on screening programmes. To achieve these goals, a multiple HPV type transmission model will be built to describe the type-specific incidence and clearance of HPV infections. This model will be linked to an individual-based simulation model used for modelling the impact of screening. For HPV-related diseases other than cervical cancer and genital warts, Markov models will be developed after critical review of the role of HPV.
In the PREHDICT study, country-specific cost-effectiveness analyses will be performed for the vaccination and include determination of the vaccination age, the number of doses, the vaccination population, and the optimal catch-up vaccination age. Furthermore, the impact of vaccination on screening programmes will be assessed. This involves determination of the screening technology, screening frequency, and follow-up management of test-positive women. Special attention will be given to screening attendance and its relation to vaccination attendance.
To have models with strong empirical support, the PREHDICT team will collect the most updated data on HPV infection, HPV-related disease, life-style factors, and demographics. Furthermore, HPV-type specific analyses will be performed on the outcomes of a vaccination trial, 3 large screening trials, and one self-sampling trial for screening non-attenders. By meta-analytical techniques, results will be pooled. The costs involved in the calculations will include the costs of organizing, running, and monitoring a vaccination and/or screening programme.
The results of the PREHDICT study will be published in international peer-reviewed journals, posted on the WHO HPV information centre website and will also be systematically disseminated to all major stakeholders, in particular to decision makers at European, national and sub-national levels.
Achievements:
General information:
Project Details
Start date:2010-05-01
End date:2013-04-30
Duration:36 months
Project Reference:242061
Project cost:3787053 EURO
Project Funding:2963532 EURO
Programme Acronym:
FP7-HEALTH
Programme type:Seventh Framework Programme
Subprogramme Area:Human Papillomavirus Vaccination (HPV) and cervical cancer screening programmes: estimate of impact of different policy options by way of disease modelling and health economics
Contract type:Small or medium-scale focused research project
URL:
Subject index:Social Aspects, Medicine, Health, Policies
Other participants
| Organization name:LUNDS UNIVERSITET | |
| Administrative contact | Address |
|
Name:Joakim |
Paradisgatan 5c 117 LUND SVERIGE Region:SVERIGE SYDSVERIGE Malmöhus län |
| Tel:+46-40-338126 | |
| Fax:+46-40-337312 | |
| E-mail:Contact | |
| URL:http://www.lu.se | Organization Type:Education |
| Organization name:LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE | |
| Administrative contact | Address |
|
Name:Penny |
KEPPEL STREET LONDON UNITED KINGDOM Region:SOUTH EAST (UK) GREATER LONDON |
| Tel:+44-2079272678 | |
| Fax:+44-2075805636 | |
| E-mail:Contact | |
| URL: | Organization Type:Education,Other |
| Organization name:IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE | |
| Administrative contact | Address |
|
Name:Michael |
Exhibition Road, South Kensington Campus LONDON UNITED KINGDOM Region:SOUTH EAST (UK) GREATER LONDON |
| Tel:+44-02075943866 | |
| Fax:+44-20-75943282 | |
| E-mail:Contact | |
| URL:http://www.imperial.ac.uk | Organization Type:Education |
| Organization name:FUNDACIO PRIVADA INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE | |
| Administrative contact | Address |
|
Name:Victoria |
AV. GRAN VIA DE L HOSPITALET 00199 HOSPITALET ESPAÑA Region: |
| Tel:+34-932607226 | |
| Fax:+34-932607224 | |
| E-mail:Contact | |
| URL:http://www.idibell.cat | Organization Type: |
| Organization name:EUROPEAN CERVICAL CANCER ASOCIATION | |
| Administrative contact | Address |
|
Name:Philip |
cours Albert Thomas 68 LYON FRANCE Region:CENTRE-EST RHÔNE-ALPES Rhône |
| Tel:+32-25382833 | |
| Fax:+32-25382833 | |
| E-mail:Contact | |
| URL:http://www.ecca.info | Organization Type: |
| Organization name:INSTITUT SCIENTIFIQUE DE SANTE PUBLIQUE | |
| Administrative contact | Address |
|
Name:Marc |
Rue Juliette Wytsman 14 BRUXELLES BELGIQUE-BELGIË Region:REG.BRUXELLES-CAP./BRUSSELS HFDST. GEW. |
| Tel:+32-2-6425111 | |
| Fax:+32-2-6425001 | |
| E-mail:Contact | |
| URL:http://www.iph.fgov.be | Organization Type: |
| Organization name:AZIENDA OSPEDALIERA SAN GIOVANNI BATTISTA DI TORINO | |
| Administrative contact | Address |
|
Name:Guglielmo |
Corso Bramante 88 TORINO ITALIA Region:NORD OVEST PIEMONTE Torino |
| Tel:+39-0116333850 | |
| Fax:+39-0116333861 | |
| E-mail:Contact | |
| URL:http://www.molinette.piemonte.it | Organization Type: |
| Organization name:TAMPEREEN YLIOPISTO | |
| Administrative contact | Address |
|
Name:Hannele |
Kalevantie 4 TAMPERE SUOMI/FINLAND Region:MANNER-SUOMI ETELÄ-SUOMI Pirkanmaa |
| Tel:+358-335516015 | |
| Fax:+358-335518970 | |
| E-mail:Contact | |
| URL:http://www.uta.fi | Organization Type:Education |
| Organization name:KAROLINSKA INSTITUTET | |
| Administrative contact | Address |
|
Name:Agneta |
Nobels Vag 5 STOCKHOLM SVERIGE Region:SVERIGE STOCKHOLM |
| Tel:+46-852486089 | |
| Fax:+46-8314975 | |
| E-mail:Contact | |
| URL:http://www.ki.se | Organization Type:Education |
Record control number:94423
