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Artificial vascularised scaffolds for 3D-tissue-regeneration
Start date:2011-11-01
End date:2015-10-31
Project Acronym:ARTIVASC 3D
Project status:Execution
Coordinator
| Organization name:FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V | |
| Administrative contact | Address |
|
Name:Walter |
Hansastrasse MUNCHEN DEUTSCHLAND Region:BAYERN OBERBAYERN München, Kreisfreie Stadt |
| Tel:+49-8912052713 | |
| Fax:+49-8912057534 | |
| E-mail:Contact | |
| URL:http://www.fraunhofer.de | Organization Type: |
Description
Objective:
The use of bioartificial tissue for regenerative medicine offers great therapeutic potential, but also has to meet high demands with respect to the interaction of the bioartificial devices and natural tissues. Key issues for the successful use of bioartifical tissues as natural tissue replacements are their long term functional stability and biocompatible integration. Up to now, various approaches for the generation of bioartificial tissues have not succeeded due to insufficient nutrition and oxygen supply. Therefore, current tissue engineered products have only been realised for non vascularised tissues such as cartilage. ArtiVasc 3D will break new ground and overcome these challenges by providing a micro- and nano-scale based manufacturing and functionalisation technology for the generation of fully vascularised bioartificial tissue that enables entire nutrition and metabolism. The bioartificial vascularised skin engineered in ArtiVasc 3D will, for the first time, allow tissue replacement with optimum properties. ArtiVasc 3D will research and develop an innovative combination of hi-tech engineering such as micro-scale printing, nano-scale multiphoton polymerisation and electro-spinning with biological research on biochemical surface modification and complex cell culture. In a multidisciplinary approach, experts in biomaterial development, cell-matrix interaction, angiogenesis, tissue engineering, simulation, design and fabrication methods work together to generate bioartificial vascularised skin in a fully automated and standardised manufacturing approach. This bioartificial vascularised skin will be of great value in a vast array of clinical treatments, e.g. as a transplant in trauma treatment. In addition, this new bioartificial vascularised skin will be used as an innovative in vitro skin equivalent for pharmaceutical, cosmetics or chemical substance testing, which represents a promising method to reduce expensive, ethically disputed animal testing.
Achievements:
General information:
Project Details
Start date:2011-11-01
End date:2015-10-31
Duration:48 months
Project Reference:263416
Project cost:10523108 EURO
Project Funding:7800000 EURO
Programme Acronym:
FP7-NMP
Programme type:Seventh Framework Programme
Subprogramme Area:Development of standard scaffolds for the rational design of bioactive materials for tissue regeneration
Contract type:Large-scale integrating project
URL:
Subject index:Materials Technology
Other participants
| Organization name:LOUGHBOROUGH UNIVERSITY | |
| Administrative contact | Address |
|
Name:Raymond |
Ashby Road LOUGHBOROUGH UNITED KINGDOM Region:EAST MIDLANDS LEICESTERSHIRE, NORTHAMPTONSHIRE Leicestershire |
| Tel:+44-1509222456 | |
| Fax:+44-1509223953 | |
| E-mail:Contact | |
| URL:http://www.lboro.ac.uk | Organization Type:Education |
| Organization name:MEDIZINISCHE UNIVERSITAET WIEN | |
| Administrative contact | Address |
|
Name:Ferdinand |
SPITALGASSE 23 WIEN ÖSTERREICH Region:OSTÖSTERREICH WIEN |
| Tel:+43-1404006896 | |
| Fax:+43-1404006898 | |
| E-mail:Contact | |
| URL:http://www.meduniwien.ac.at | Organization Type: |
| Organization name:UNIVERSITY OF EAST ANGLIA | |
| Administrative contact | Address |
|
Name:Alan |
EARLHAM ROAD NORWICH UNITED KINGDOM Region:EAST ANGLIA Norfolk |
| Tel:+44-1603591481 | |
| Fax: | |
| E-mail:Contact | |
| URL:http://www.uea.ac.uk | Organization Type: |
| Organization name:ARTTIC | |
| Administrative contact | Address |
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Name:Martin |
Rue du Dessous des Berges PARIS FRANCE Region:ÎLE DE FRANCE Ile de France Paris |
| Tel:+49-8957868677 | |
| Fax: | |
| E-mail:Contact | |
| URL:http://www.arttic.fr | Organization Type: |
| Organization name:ALBERT-LUDWIGS-UNIVERSITAET FREIBURG | |
| Administrative contact | Address |
|
Name:Michael |
FAHNENBERGPLATZ FREIBURG DEUTSCHLAND Region:BADEN-WÜRTTEMBERG FREIBURG Freiburg im Breisgau, Stadtkreis |
| Tel:+49-7612037695 | |
| Fax:+49-7615142403 | |
| E-mail:Contact | |
| URL:http://www.uni-freiburg.de | Organization Type:Education |
| Organization name:UNIVERSITAET STUTTGART | |
| Administrative contact | Address |
|
Name:Günter |
Keplerstrasse STUTTGART DEUTSCHLAND Region:BADEN-WÜRTTEMBERG STUTTGART Stuttgart, Stadtkreis |
| Tel:+49-7119704109 | |
| Fax: | |
| E-mail:Contact | |
| URL: | Organization Type: |
| Organization name:UNIVERSITA DEGLI STUDI DI SALERNO | |
| Administrative contact | Address |
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Name:Loredana |
VIA PONTE DON MELILLO FISCIANO (SA) ITALIA Region: |
| Tel:+39-089964019 | |
| Fax:+39-089964057 | |
| E-mail:Contact | |
| URL:http://www.unisa.it | Organization Type: |
| Organization name:SYSMELEC S.A. | |
| Administrative contact | Address |
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Name:Ivan |
Route de Berne GALS SCHWEIZ/SUISSE/SVIZZERA Region:ESPACE MITTELLAND Bern |
| Tel:+41-323388585 | |
| Fax:+41-323388601 | |
| E-mail:Contact | |
| URL:http://www.sysmelec.ch | Organization Type: |
| Organization name:KMS AUTOMATION GMBH | |
| Administrative contact | Address |
|
Name:Thomas |
Im Webertal SCHRAMBERG-WALDMOESSSINGEN DEUTSCHLAND Region: |
| Tel:+49-74029306132 | |
| Fax:+49-74029306110 | |
| E-mail:Contact | |
| URL:http://www.kms-kemmer.de | Organization Type: |
| Organization name:AALTO-KORKEAKOULUSAATIO | |
| Administrative contact | Address |
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Name:Minna |
OTAKAARI 00076 AALTO SUOMI/FINLAND Region: |
| Tel:+358-947022620 | |
| Fax: | |
| E-mail:Contact | |
| URL:http://www.aalto.fi/en/ | Organization Type: |
| Organization name:VEREIN ZUR FORDERUNG VON INNOVATIONEN DURCH FORSCHUNG ENTWICKLUNG UNDTECHNOLOGIETRANSFER EV | |
| Administrative contact | Address |
|
Name:Ralf |
PRUESSINGSTRASSE JENA DEUTSCHLAND Region:THÜRINGEN Thuringen Jena, Kreisfreie Stadt |
| Tel:+49-3641282563 | |
| Fax:+49-3641282530 | |
| E-mail:Contact | |
| URL:http://www.innovent-jena.de | Organization Type: |
| Organization name:BEIERSDORF AG | |
| Administrative contact | Address |
|
Name:Wolfgang |
UNNASTRASSE HAMBURG DEUTSCHLAND Region:HAMBURG |
| Tel:+49-4049093157 | |
| Fax: | |
| E-mail:Contact | |
| URL:http://www.beiersdorf.com | Organization Type: |
| Organization name:BERUFSGENOSSENSCHAFLICHES UNIVERSITAETSKLINIKUM BERGMANNSHEIL GMBH | |
| Administrative contact | Address |
|
Name:Frank |
BUERKLE-DE-LA-CAMP-PLATZ BOCHUM DEUTSCHLAND Region:NORDRHEIN-WESTFALEN ARNSBERG Bochum, Kreisfreie Stadt |
| Tel:+49-2343023542 | |
| Fax:+49-2343252080 | |
| E-mail:Contact | |
| URL: | Organization Type: |
| Organization name:VIMECON GMBH | |
| Administrative contact | Address |
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Name:Markus |
KAISERSTRASSE HERZOGENRATH DEUTSCHLAND Region:NORDRHEIN-WESTFALEN KÖLN Köln, Kreisfreie Stadt |
| Tel:+49-2407555990 | |
| Fax: | |
| E-mail:Contact | |
| URL:http://www.vimeon.com | Organization Type: |
| Organization name:GLOBAL CLINICAL TRIALS MANAGEMENT AG | |
| Administrative contact | Address |
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Name:Stephan |
GRABENSTRASSE CHUR SCHWEIZ/SUISSE/SVIZZERA Region:OSTSCHWEIZ Graubünden |
| Tel:+41-814142211 | |
| Fax: | |
| E-mail:Contact | |
| URL:http://www.gctm.com | Organization Type: |
Record control number:101209
