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European challenge for healthy ageing (ECHA)
Start date:2002-01-01
End date:2004-12-31
Project Acronym:ECHA
Project status:Completed
Coordinator
| Organization name:UNIVERSITA DEGLI STUDI DELLA CALABRIA | |
| Administrative contact | Address |
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Name:Giovanni |
DIPARTIMENTO DI BIOLOGIA CELLULARE Ponte Pietro Bucci, Arcavacata 87036 RENDE ITALIA Region:SUD CALABRIA Cosenza |
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| URL: | Organization Type:Education |
Description
Objective:
Frailty is emerging as a major characteristic of elderly people. It is characterised by an impending disability and high risk of morbidity and mortality. The relative impact of environment and genetics on frailty is presently unknown. This question will be addressed by assuming that frailty is low in centenarians' children and by comparing couples of cousins 60-80 years old born from discordant sib pairs as for age of death (one centenarian and his/her sib died at relatively young age) with couples of cousins born from concordant sib pairs (both sibs dead at ages which do not differ more than 5 years). In these samples the unbalance of genetic transmission of alleles of genes related to the stress response will be assessed and compared with measures of frailty (motor and cognitive disabilities) expressed as "frailty index". This approach should help defining risk profiles of healthy/unhealthy ageing in the population.
Achievements:
General information:
Project Details
Start date:2002-01-01
End date:2004-12-31
Duration:36 months
Project Reference:QLK6-CT-2001-00128
Project cost:1157325 EURO
Project Funding:1157325 EURO
Programme Acronym:
FP5-LIFE QUALITY
Programme type:Fifth Framework Programme
Subprogramme Area:Key action The Ageing Population and Disabilities
Contract type:Cost-sharing contracts
URL:
Subject index:Medicine, Health, Life Sciences, Social Aspects
Other participants
| Organization name:UNIVERSITY OF SOUTHERN DENMARK - UNIVERSITY OF ODENSE | |
| Administrative contact | Address |
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Name:Vagn |
INSTITUTE OF HEALTH SERVICES RESEARCH Winsleowparken, 19,3 5000 ODENSE DANMARK Region:DANMARK Danmark Fyns amt |
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| URL: | Organization Type:Education |
| Organization name:UNIVERSITY OF BOLOGNA | |
| Administrative contact | Address |
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Name:Claudio |
C.I.G. - CENTRO INTERDIPARTIMENTALE "L. GALVANI" PER STUDI INTEGRATI DI BIOINFORMATICA, BIOFISICA E BIOCOMPLESSITÀ Via Tolara di Sopra 50 40064 OZZANO DELL EMILIA ITALIA Region:EMILIA-ROMAGNA Bologna |
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| URL: | Organization Type:Education |
| Organization name:CENTRE REGIONAL DE LUTTE CONTRE LE CANCER DE MONTPELLIER | |
| Administrative contact | Address |
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Name:Jean-Bernard |
DÉMOGRAPHIE ET SANTÉ - EQUIPE INSERM Val d'Aurelle - Parc Euromédecine 34298 MONTPELLIER FRANCE Region:MÉDITERRANÉE LANGUEDOC-ROUSSILLON Hérault |
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| URL: | Organization Type:Research,Other |
| Organization name:MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. | |
| Administrative contact | Address |
|
Name:James |
MAX PLANCK INSTITUTE FOR DEMOGRAPHIC RESEARCH, ROSTOCK LABORATORY FOR ADVANCED STATISTICAL METHODS Doberaner Strasse 114 18057 ROSTOCK DEUTSCHLAND Region:MECKLENBURG-VORPOMMERN Mecklenburg-Vorpommern Rostock, Kreisfreie Stadt |
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| URL: | Organization Type:Research |
Record control number:60277
