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Scanning probe microscopy techniques for real time, high resolution imaging and molecular recognition in functional and structural genomics
Start date:2005-02-01
End date:2008-07-31
Project Acronym:TIPS4CELLS
Project status:Completed
Coordinator
| Organization name:UNIVERSITEIT LEIDEN | |
| Administrative contact | Address |
|
Name:Tjerk Hendrik |
LEIDEN INSTITUTE OF PHYSICS, DEPARTMENT OF CONDENSED MATTER Rapenburg 70 LEIDEN NEDERLAND Region:WEST-NEDERLAND ZUID-HOLLAND Agglomeratie Leiden en Bollenstreek |
| Tel:+31-715-275-424 | |
| Fax:+31-715-275-404 | |
| E-mail:Contact | |
| URL:http://www.physics.leidenuniv.nl | Organization Type:Other |
Description
Objective:
High resolution ¡maging of living cells and subcellular components is essential for functional and structural genomics'. Scanning Probe Microscopy (SPM) has evolved into the imaging method of choice that yields the greatest structural details on biological samples such as proteins, nucleotides, membranes and cells in their native, aqueous environment and at ambient conditions. In addition, due to its high lateral resolution and sensitive force detection capability, the exciting possibility of measuring inte r- and intra-molecular forces of bio-molecules on the single molecule level has become possible, leading to new possibilities for the evolution of methods that will enable us to examine the physiological consequences of, even, the interaction of a single l igand molecule with its cognate receptor. In this project we propose to develop Scanning Probe Microscopy to advance the state of the art of this technique. With the support of the Sixth Framework program, Scanning Probe Microscopy is ready to become a mat ure imaging and measurement platform for cell biology that will become as widespread in the biomedicai laboratory as the confocal microscope, adding value to the European scientific instrument market and giving it a major presence worldwide.'
Achievements:
General information:
Project Details
Start date:2005-02-01
End date:2008-07-31
Duration:42 months
Project Reference:512101
Project cost:1945000 EURO
Project Funding:1713000 EURO
Programme Acronym:
FP6-LIFESCIHEALTH
Programme type:Sixth Framework Programme
Subprogramme Area:Topics for Specific Targeted Research Project in the area of Fundamental knowledge and basic tools for functional genomics in all organisms, Structure determination of large protein complexes
Contract type:Networks of Excellence
URL:
Subject index:Life Sciences, Biotechnology, Medicine, Health
Other Indexes:Microscopy,Force,Scanning
Results for this Project
| Final Report Summary - TIPS4CELLS (Scanning probe microscopy techniques for real-time, high-resolution imaging and molecular recognition in functional and structural genomics) | 14/04/2011 |
Documents for this Project
| Final Report - TIPS4CELLS (Scanning probe microscopy techniques for real-time, high-resolution imaging and molecular recognition in functional and structural genomics) | 14/04/2011 |
Other participants
| Organization name:JOHANNES KEPLER UNIVERSITÄT LINZ | |
| Administrative contact | Address |
|
Name:Peter |
INSTITUTE FOR BIOPHYSICS Altenbergerstr. 69 LINZ ÖSTERREICH Region:WESTÖSTERREICH OBERÖSTERREICH Linz-Wels |
| Tel:+43-73224689265 | |
| Fax:+43-73224689270 | |
| E-mail:Contact | |
| URL:http://at22.bphys.uni-linz.ac.at/bioph/res/afm/index.html | Organization Type:Research |
| Organization name:WEIZMANN INSTITUTE OF SCIENCE | |
| Administrative contact | Address |
|
Name:Ziv |
BIOLOGICAL CHEMISTRY/BIOCHEMISTRY/WEIZMANN INSTITUTE OF SCIENCE Herzelstreet 2 REHOVOT ISRAEL Region: |
| Tel:+972-8-9342982 | |
| Fax:+972-8-9346010 | |
| E-mail:Contact | |
| URL:http://www.weizmann.ac.il | Organization Type:Other |
| Organization name:UNIVERSITY COLLEGE LONDON | |
| Administrative contact | Address |
|
Name:Michael Anthony |
BONE AND MINERAL CENTRE, DEPARTMENT OF MEDICINE, ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL Gower Street LONDON UNITED KINGDOM Region:SOUTH EAST (UK) GREATER LONDON |
| Tel:+44-2076796169 | |
| Fax:+44-2076796219 | |
| E-mail:Contact | |
| URL:http://www.ucl.ac.uk | Organization Type:Other |
| Organization name:UNIVERSITY OF BRISTOL | |
| Administrative contact | Address |
|
Name:Mervyn |
PHYSICS DEPARTMENT, UNIVERSITY OF BRISTOL Senate House, Tyndall Avenue BRISTOL UNITED KINGDOM Region:SOUTH WEST (UK) AVON, GLOUCESTERSHIRE, WILTSHIRE Avon |
| Tel:+44-1179288207 | |
| Fax:+44-1179255624 | |
| E-mail:Contact | |
| URL:http://www.bristol.ac.uk | Organization Type:Other |
| Organization name:JPK INSTRUMENTS AG | |
| Administrative contact | Address |
|
Name:Torsten |
JPK INSTRUMENTS AG Bouchéstrasse 12, Haus 8, Aufgang B BERLIN DEUTSCHLAND Region:BERLIN |
| Tel:+49-30533112074 | |
| Fax:+49-3053311202 | |
| E-mail:Contact | |
| URL:http://www.jpk.com | Organization Type:Industry |
| Organization name:SCIENTEC | |
| Administrative contact | Address |
|
Name:Sam |
SCIENTEC 2 Allee de Garays ZAE des Glaises PALAISEAU FRANCE Region:ÎLE DE FRANCE Ile de France Essonne |
| Tel:+33-164532700 | |
| Fax:+33-164532701 | |
| E-mail: | |
| URL:http://www.molec.com | Organization Type:Industry |
| Organization name:LEIDEN PROBE MICROSCOPY | |
| Administrative contact | Address |
|
Name:Marcel |
KAMERLINGH ONNES LABORATORIUM PO Box 9504 Niels Bohrweg 2 LEIDEN NEDERLAND Region:WEST-NEDERLAND ZUID-HOLLAND Agglomeratie Leiden en Bollenstreek |
| Tel:+31-715275600 | |
| Fax:+31-715275404 | |
| E-mail: | |
| URL:http://www.leidenprobemicroscopy.com | Organization Type:Industry |
| Organization name:WESTFÄLISCHE WILHELMS UNIVERSITÄT MÜNSTER | |
| Administrative contact | Address |
|
Name:Hans |
INSTITUTE OF PHYSIOLOGY II INSTITUTE OF PHYSIOLOGY Schlossplatz 2 MUENSTER DEUTSCHLAND Region:NORDRHEIN-WESTFALEN MÜNSTER Münster, Kreisfreie Stadt |
| Tel:+49-02518355540 | |
| Fax:+49-02518355331 | |
| E-mail:Contact | |
| URL:http://www.klinikum.uni-muenster.de | Organization Type: |
| Organization name:AGILENT TECHNOLOGIES ÖSTENRREICH GMBH | |
| Administrative contact | Address |
|
Name:Gerald |
AGILENT TECHNOLOGIES LINZ, NANO MEASUREMENT DIVISION (NMD) Dresdner Strasse 81-85 VIENNA ÖSTERREICH Region:OSTÖSTERREICH WIEN |
| Tel:+43-73224681585 | |
| Fax:+43-73224689270 | |
| E-mail:Contact | |
| URL:http://www.agilent.com | Organization Type:Industry |
Record control number:75694
