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Intelligent nanocomposite for bone tissue repair and regeneration
Start date:2005-05-01
End date:2008-06-30
Project Acronym:NANOBIOCOM
Project status:Completed
Coordinator
| Organization name:FUNDACION INASMET | |
| Administrative contact | Address |
|
Name:Jose Iñaki |
MATERIALS AND PROCESSES MIKELETEGI PASEALEKUA, 2- PARQUE TECNOLGICO DONOSTIA-SAN SEBASTIAN ESPAÑA Region: |
| Tel:+34-943003700 | |
| Fax:+34-943003800 | |
| E-mail:Contact | |
| URL:http://WWW.INASMET.ES | Organization Type:Research |
Description
Objective:
There are roughly 1 million cases in the USA and 1/2 million in EU of high skeletal defects a year. All of these cases require bone-graft procedures to achieve union, each of which require the surgeon to determine the type of graft material to be use. The toughest challenge appears when the size of the defect is too big and the reconstruction of this defect requires a bone graft capable of supplying similar physical properties and behavior to the bone being substituted. Unfortunately at this moment commerci al scaffolds can not satisfy the following issues: * To promote new bone formation in order to reduce the time of bone healing and decrease the vascular insult of the implant to the bone and cause less-stress shielding. * Mechanical properties that match t hose of human tissue to be regenerated during its new formation. * Regeneration of Large segment of implants. For patients who have lost large segments of bone due to a congenital defect, degenerative diseases, cancer or accident. Based on these basic need s to provide an ideal scaffold, the NANOBIOCOM project aims at establishing the scientific and technological basis for the development new "intelligent" composite scaffold for bone tissue repair and regeneration with the following issues: + Bioactive behavior capable of activating osteoprogenitor cells and genes and within an in vivo mileu provide the interface to respond to physiological and biological changes, + Mechanical and structural properties similar to a healthy bone. +Size and shape required for reconstructing big skeletal defects Concerning one potential application of the NANOBIOCOM project developments, it can be emphasized that the average age in Europe increases and aged people account for a higher proportion of the population, the nation can expect the $15 billion to $18 billion spent each for the treatment of bone and joint conditions to more than double as well.
Achievements:
General information:
Project Details
Start date:2005-05-01
End date:2008-06-30
Duration:38 months
Project Reference:516943
Project cost:2876175 EURO
Project Funding:2017616 EURO
Programme Acronym:
FP6-NMP
Programme type:Sixth Framework Programme
Subprogramme Area:Technologies associated with the production, transformation and processing of knowledge-based multifunctional materials, Intelligent' bio-materials for tissue repair and regeneration
Contract type:Specific Targeted Innovation Project
URL:
Subject index:Electronics, Microelectronics, Biotechnology, Life Sciences, Medicine, Health
Other Indexes:Nanotechnology
Results for this Project
| Final Report Summary - NANOBIOCOM (Intelligent nanocomposite for bone tissue repair and regeneration) | 14/04/2011 |
Documents for this Project
| Final Report - NANOBIOCOM (Intelligent nanocomposite for bone tissue repair and regeneration) | 14/04/2011 |
Other participants
| Organization name:UNIVERSITY OF ABERDEEN | |
| Administrative contact | Address |
|
Name:Colin |
SCHOOL OF MEDICAL SCIENCES, INSTITUTE OF MEDICAL SCIENCES Kings College ABERDEEN UNITED KINGDOM Region:SCOTLAND GRAMPIAN |
| Tel:+44-1224555747 | |
| Fax:+44-1224555719 | |
| E-mail:Contact | |
| URL:http://www.abdn.ac.uk/ | Organization Type:Other |
| Organization name:CONSORZIO INTERUNIVERSITARIO NAZIONALE PER LA SCIENZA E TECNOLOGIA DEI MATERIALI | |
| Administrative contact | Address |
|
Name:Jose M. |
INSTM RES. UNIT OF PERUGIA - DEPT. OF MATERIALS SCIENCE AND TECHNOLOGY - UNIVERSITY OF PERUGIA VIA BENEDETTO VARCHI, 59 FLORENCE ITALIA Region: |
| Tel:+39-0744-492939 | |
| Fax:+39-0744-492925 | |
| E-mail:Contact | |
| URL:http://www.instm.it | Organization Type:Research |
| Organization name:STICHTING KATHOLIEKE UNIVERSITEIT | |
| Administrative contact | Address |
|
Name:Johannus Arnoldus |
THK 117 - PERIODONTOLOGY & BIOMATERIALS PO BOX 9101 Geert Grooteplein 10 NIJMEGEN NEDERLAND Region:OOST-NEDERLAND GELDERLAND Arnhem/Nijmegen |
| Tel:+31-243614006 | |
| Fax:+31-243614657 | |
| E-mail:Contact | |
| URL:http://www.umcn.nl | Organization Type:Education |
| Organization name:ISTITUTI ORTOPEDICI RIZZOLI | |
| Administrative contact | Address |
|
Name:Gabriela |
LABORATORIO DI FISIOPATOLOGIA DEGLI IMPIANTI ORTOPEDICI - LABORATORY FOR PATHOPHYSIOLOGY OF ORTHOPAEDIC IMPLANTS Via di Barbiano 1/10 BOLOGNA ITALIA Region:EMILIA-ROMAGNA Bologna |
| Tel:+39-0516366897 | |
| Fax:+39-0516366748 | |
| E-mail:Contact | |
| URL:http://www.ior.it/ | Organization Type:Research |
| Organization name:INSTITUTO DE BIOMECÁNICA DE VALENCIA | |
| Administrative contact | Address |
|
Name:José L. |
R+D AREA. IMPLANT SECTION Universidad Politécnica de Valencia. Edificio 9C. Camino de Vera s/n. VALENCIA ESPAÑA Region:ESTE COMUNIDAD VALENCIANA Valencia |
| Tel:+34-963879160 | |
| Fax:+34-963879169 | |
| E-mail:Contact | |
| URL:http://www.ibv.org | Organization Type:Research |
| Organization name:ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE | |
| Administrative contact | Address |
|
Name:Jacques |
EPFL STI IMX LTP Ecublens LAUSANNE SCHWEIZ/SUISSE/SVIZZERA Region:RÉGION LÉMANIQUE Vaud |
| Tel:+41-216933601 | |
| Fax:+41-216933089 | |
| E-mail:Contact | |
| URL:http://WWW.EPFL.CH | Organization Type:Education |
| Organization name:PROGENIKA BIOPHARMA S.A. | |
| Administrative contact | Address |
|
Name:Corina |
RESEARCH DEPARTMENT PARQUE TECNOLOGICO DE ZAMUDIO, Edif. 801, 2Planta DERIO-VIZCAYA ESPAÑA Region: |
| Tel:+34-944064525 | |
| Fax:+34-944064526 | |
| E-mail:Contact | |
| URL:http://WWW.PROGENIKA.COM | Organization Type:Industry |
Record control number:75847
