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Nanobiotechnology for the coating of medical devices
Start date:2005-04-01
End date:2008-03-31
Project Acronym:PECTICOAT
Project status:Completed
Coordinator
| Organization name:DIVERGENT SA - GROUPE UTC | |
| Administrative contact | Address |
|
Name:Marie-Danielle |
DIVERGENT SA BP 50149 Centre de Transfert - Rond Point Guy Denielou, 66 avenue de Landshut COMPIEGNE FRANCE Region:BASSIN PARISIEN PICARDIE Oise |
| Tel:+33-344-234-423 | |
| Fax:+33-344-204-813 | |
| E-mail:Contact | |
| URL:http://www.divergent.fr/ | Organization Type:Other |
Description
Objective:
Surfaces of medical materials and devices that come into direct contact with human tissues need to be fine-tuned with regard to both physical and biological properties. A cross-disciplinary nanotechnology approach is proposed that aims to impart material surfaces with appropriate biological properties. This approach gathers competences from across Europe and includes a critical mass of resources necessary to accelerate the R&D process. The biomolecules that are to be grafted onto surfaces to functio n as nanocoatings have been selected from a class of complex polysaccharides, the pectic rhamnogalacturonans, that are known to possess anti-inflammatory properties as well as desirable physical properties. Sugar molecular structure will be altered in a controlled manner so as to favourably influence living cell behaviour around the coated materials. Current knowledge and expertise within our project team covers technologies to manufacture a range of tailored polysaccharides, to attach the molecules co valently to relevant biomaterials (e.g. titanium for dental implants) and to characterize the grafted surfaces and to assess their biocompatibility both in vitro and in vivo. We expect to generate evidence demonstrating both the antiinflammatory and mole cular flexibility of the innovative nanocoatings. This will open a platform for the development of a large range of applications that will be defined through industrial guidance and result in solutions for current bioincompatibility problems of various i mplantable devices. Industrial monitoring and engineering will allow the exploration of a wide range of applications (breast implants, meshes etc.). For one of these: the dental application, the involvement of industrial SMEs covers the full production c hain from raw material to prototype design which will lead in to a demonstration phase.
Achievements:
General information:
Project Details
Start date:2005-04-01
End date:2008-03-31
Duration:36 months
Project Reference:517036
Project cost:2852613 EURO
Project Funding:1850000 EURO
Programme Acronym:
FP6-NMP
Programme type:Sixth Framework Programme
Subprogramme Area:Intelligent' bio-materials for tissue repair and regeneration, New knowledge on interfaces for new applications
Contract type:Specific Targeted Innovation Project
URL:
Subject index:Electronics, Microelectronics, Medicine, Health, Biotechnology, Life Sciences, Industrial Manufacture, Scientific Research
Other Indexes:Nanotechnology
Results for this Project
| Final Report Summary - PECTICOAT (Nanobiotechnology for the coating of medical devices) | 14/04/2011 |
Documents for this Project
| Final Report - PECTICOAT (Nanobiotechnology for the coating of medical devices) | 14/04/2011 |
| Nanobiotechnology for the coating of medical devices (PectiCoat) - Publishable Executive Summary | 30/10/2008 |
Other participants
| Organization name:DANISH INSTITUTE OF AGRICULTURAL SCIENCES | |
| Administrative contact | Address |
|
Name:Peter |
BIOTECHNOLOGY GROUP PO Box 50 Blichers Alle 20 TJELE DANMARK Region:DANMARK Danmark Viborg amt |
| Tel:+45-35282580 | |
| Fax:+45-35282589 | |
| E-mail:Contact | |
| URL:http://www.agrsci.dk | Organization Type:Research |
| Organization name:NOBIL BIO RICERCHE S.R.L. | |
| Administrative contact | Address |
|
Name:Marco |
NOBIL BIO RICERCHE S.R.L. Strada San Rocco 36 VILLAFRANCA D'ASTI' ITALIA Region: |
| Tel:+39-0141942446 | |
| Fax:+39-0141941956 | |
| E-mail:Contact | |
| URL:http://www.nobilbio.it | Organization Type:Industry |
| Organization name:STATICE SANTE | |
| Administrative contact | Address |
|
Name:Serge |
STATICE SANTE 9 RUE THOMAS EDISON BESANCON FRANCE Region:EST FRANCHE-COMTÉ Doubs |
| Tel:+33-381484335 | |
| Fax:+33-381480901 | |
| E-mail:Contact | |
| URL:http://www.statice.com | Organization Type:Industry |
| Organization name:UNIVERSITE DE TECHNOLOGIE DE COMPIEGNE | |
| Administrative contact | Address |
|
Name:Marie-Danielle |
BIOMCANIQUE ET GENIE BIOMDICAL - UMR UTC CNRS 6600 BP 60319 Centre Benjamin Franklin, Rue Roger Couttolenc COMPIEGNE FRANCE Region:BASSIN PARISIEN PICARDIE Oise |
| Tel:+33-344-234-423 | |
| Fax:+33-344-204-813 | |
| E-mail:Contact | |
| URL:http://www.utc.fr | Organization Type:Education |
| Organization name:EUROPEAN COMMISSION, JOINT RESEARCH CENTRE | |
| Administrative contact | Address |
|
Name:Giacomo |
INSTITUTE FOR HEALTH AND CONSUMER PROTECTION/ BMS UNIT/SCP SECTOR Rue de la Loi 200 BRUXELLES BELGIQUE-BELGIË Region:REG.BRUXELLES-CAP./BRUSSELS HFDST. GEW. |
| Tel:+39-0332785475 | |
| Fax:+39-0332785787 | |
| E-mail:Contact | |
| URL:http://www.jrc.cec.eu.int | Organization Type:Research |
| Organization name:UNIVERSITY OF OULU | |
| Administrative contact | Address |
|
Name:Juha |
DEPARTMENT OF ANATOMY AND CELL BIOLOGY PO Box 8000 Pentti Kaiteran katu 1 OULU SUOMI/FINLAND Region:MANNER-SUOMI POHJOIS-SUOMI Pohjois-Pohjanmaa |
| Tel:+358-85375163 | |
| Fax:+358-85375172 | |
| E-mail:Contact | |
| URL:http://www.oulu.fi | Organization Type:Education |
| Organization name:WAGENINGEN UNIVERSITY | |
| Administrative contact | Address |
|
Name:Henk |
DEPARTMENT OF AGROTECHNOLOGY AND FOOD SCIENCES, FOOD CHEMESTRY GROUP PO Box 9101 Costerweg 50 WAGENINGEN NEDERLAND Region:OOST-NEDERLAND GELDERLAND Arnhem/Nijmegen |
| Tel:+31-0317482239 | |
| Fax:+31-0317484893 | |
| E-mail:Contact | |
| URL:http://ww.wur.nl | Organization Type:Education |
| Organization name:POALIS A/S | |
| Administrative contact | Address |
|
Name:Ole Rye |
POALIS A/S Bulowsvej 25 FREDERIKSBERG DANMARK Region:DANMARK Danmark København og Frederiksberg Kommuner |
| Tel:+45-26872425 | |
| Fax:+45-35288385 | |
| E-mail:ole.rye.jensen@poalis | |
| URL:http://www.poalis.dk | Organization Type:Industry |
| Organization name:UNIVERSITY OF LEEDS | |
| Administrative contact | Address |
|
Name:John Paul |
CENTRE FOR PLANT SCIENCES / FACULTY OF BIOLOGICAL SCIENCES Woodhouse Lane LEEDS UNITED KINGDOM Region:YORKSHIRE AND HUMBERSIDE WEST YORKSHIRE |
| Tel:+44-113-3433169 | |
| Fax:+44-113-3433144 | |
| E-mail:Contact | |
| URL:http://www.leeds.ac.uk | Organization Type:Education |
| Organization name:AGLIATI SRL | |
| Administrative contact | Address |
|
Name:Giovanni |
AGLIATI SRL VIA STATALE BRIANTEA KM. 12,7 PALAZZAGO ITALIA Region:LOMBARDIA Bergamo |
| Tel:+39-035549275 | |
| Fax:+39-035555990 | |
| E-mail:Contact | |
| URL:http://www.agliati.it | Organization Type:Industry |
| Organization name:UNIVERSITA' DEGLI STUDI DI TRENTO | |
| Administrative contact | Address |
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Name: |
ITALIA Region: |
| Tel: | |
| Fax: | |
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| URL: | Organization Type: |
Record control number:75859
