Community Research and Development Information Service - CORDIS

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Functional Genomics in Engineered ES cells
ID: 503494
Start date: 2004-03-01, End date: 2007-12-31
The complete sequence of a mammalian genome defines the total information content. The next major challenge is to understand how the information is used in subsets during development - subsets that define multipotential states (stem cells); subsets that define differentiated s...
Programme: FP6-LIFESCIHEALTH
Record Number: 78710
Last updated on: 2013-03-26
Flow cytometry for fast and sensitive diagnosis and follow-up of haematological malignancies
ID: 18708
Start date: 2006-04-01, End date: 2009-09-30
Laboratory diagnostics of haematological malignancies has three major applications: establishing the diagnosis, prognostic classification, and evaluation of treatment effectiveness. Over the past decade, several molecular techniques have brought new insights into classificatio...
Programme: FP6-LIFESCIHEALTH
Record Number: 84808
Last updated on: 2012-10-19
Chromatin structure and plasticity
[PROJECT] CHROMATIN PLASTICITY - Chromatin structure and plasticity
ID: 35733
Start date: 2006-10-15, End date: 2010-10-14
The mammalian genome is packaged into a dynamic structure known as chromatin. There are a range of mechanisms - often referred to as 'epigenetic' controls -that alter its structure and function. These include post-translational modifications, histone variants, and non-coding R...
Programme: FP6-MOBILITY
Record Number: 82437
Last updated on: 2012-07-24
INTEGRATED TECHNOLOGIES FOR IN-VIVO MOLECULAR IMAGING
ID: 503259
Start date: 2004-01-01, End date: 2008-12-31
The goal of the project proposed here is to generate and apply novel advanced technology for non- invasive imaging of biomolecular function in living systems ranging from single cells to whole animals. Main areas for technological innovation are i) generation of new biosensors...
Programme: FP6-LIFESCIHEALTH
Record Number: 78698
Last updated on: 2011-09-16
European alternative splicing network of excellence
ID: 518238
Start date: 2006-01-01, End date: 2011-03-31
Posttranscriptional events must play a more central role in generating the highly complex proteomes of metazoa than previously believed. This is shown by the large discrepancy between the number of coding sequences of metazoan genomes and the known diversi ty of gene products ...
Programme: FP6-LIFESCIHEALTH
Record Number: 78768
Last updated on: 2011-07-11
Promoting Support for Science and Technology - Portugal
ID: 19455
Start date: 2005-06-01, End date: 2006-03-31
The Consortium formed by the Institute of Molecular Medicine and Associação Viver a Ciência aim through this project to promote science by involving the public in scientific research. In this proposal, we set out a series of four actions throughout 2005 ai med at promoting sup...
Programme: FP6-MOBILITY
Record Number: 75081
Last updated on: 2010-01-12
Molecular mechanisms of resistance, virulence and epidemicity in Streptococcus pneumoniae. PREVIS (Pneumococcal Resistance Epidemicity and Virulence - an international study
ID: 503413
Start date: 2004-01-01, End date: 2007-06-30
Human pathogens face two main kinds of evolutionary challenges. A. Survival and growth in an antibiotic rich milieu selects for genetic traits of resistance. B. Successful drug resistant strains must also be able to compete with other members of the species for colonization, s...
Programme: FP6-LIFESCIHEALTH
Record Number: 78704
Last updated on: 2009-12-23
Unfolded protein response in mammals
ID: 29185
Start date: 2006-01-01, End date: 2006-02-28
The eukaryotic unfolded protein response (UPR) is an integrated cellular stress response that detects incorrectly folded proteins at the endoplasmic reticulum and acts to minimize their accumulation. The proteasomal degradation of misfolded proteins by ER associated degradatio...
Programme: FP6-MOBILITY
Record Number: 82844
Last updated on: 2009-12-03
CELLS INTO ORGANS: FUNCTIONAL GENOMICS FOR DEVELOPMENT AND DISEASE OF MESODERMAL ORGAN SYSTEMS
ID: 504468
Start date: 2004-04-01, End date: 2009-03-31
New approaches to treating disease are set to revolutionise health care. Cancers will increasingly be treated by targeted molecules, not cytotoxic drugs. Manipulating stem cells for cell and tissue replacement therapies holds great promise for treatment of degenerative disease...
Programme: FP6-LIFESCIHEALTH
Record Number: 75325
Last updated on: 2009-12-02
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List retrieved on: 2017-09-19
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