Community Research and Development Information Service - CORDIS

Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Investigating Hereditary Cancer Predisposition – a combined genomics approach
ID: 310018
Start date: 2013-05-01, End date: 2019-04-30
Background: Hereditary cancer is an important cause of morbidity and mortality and over the last 20 years, the majority of highly penetrant risk alleles such as BRCA1, BRCA2 in breast cancer and APC, MLH1, MSH2 in colon cancer have been identified. However, there are many men...
Programme: FP7-IDEAS-ERC
Record Number: 108266
Last updated on: 2017-11-20
Protection against reactive oxygen species in neurodegeneration
ID: 311394
Start date: 2013-02-01, End date: 2018-05-31
Oxidative stress (OS) is implicated in the pathogenesis of some of the most devastating neurological diseases. Therefore, identification of pathways that counteract oxidative damage may lead to therapeutic strategies applicable to a wide range of disorders. I have recently id...
Programme: FP7-IDEAS-ERC
Record Number: 106704
Last updated on: 2017-09-24
Molecular Mechanisms of GABAergic synapse formation: spatial segregation in cortical inhibitory inputs
ID: 310021
Start date: 2013-01-01, End date: 2018-06-30
Neuronal circuitries underlying the function of the mammalian cerebral cortex collectively constitute one of the most complex biological systems. As such, unraveling the mechanisms that control their development represents one of the most challenging questions in Science. Und...
Programme: FP7-IDEAS-ERC
Record Number: 105616
Last updated on: 2017-09-24
Endosomal dependent transport to the unique secretory organelles of apicomplexan parasites
ID: 309255
Start date: 2013-02-01, End date: 2019-01-31
Apicomplexan parasites invade the host cell in an active process that involves gliding motility, formation and movement through the moving junction (MJ) and establishment of a prasitophorous vacuole (PV) around the parasite. In order to invade the host cell they employ an ars...
Programme: FP7-IDEAS-ERC
Record Number: 105401
Last updated on: 2017-09-10
Mechanisms Underlying Treatment Responses in Psychosis
ID: 311686
Start date: 2013-03-01, End date: 2018-11-30
Psychotic symptoms (hallucinations and delusions) have been associated with a striatal hyperdopaminergic state. Less explored, but also implicated are functional abnormalities in cognitive control, particularly in the prefrontal cortex; and a functional and structural disconn...
Programme: FP7-IDEAS-ERC
Record Number: 106740
Last updated on: 2017-09-03
Dissecting the genetic basis of divergent and convergent evolution: From individuals to species radiations
ID: 310482
Start date: 2013-02-01, End date: 2019-01-31
Advances in genomics offer new opportunities for identifying loci that behave unusually against a background of neutral variation. Detecting divergent sites among related individuals and taxa can shed light on the process of adaptive divergence, from non-random mating to the ...
Programme: FP7-IDEAS-ERC
Record Number: 106425
Last updated on: 2017-08-27
Dissection of centromeric chromatin and components: A biosynthetic approach
ID: 311674
Start date: 2013-02-01, End date: 2019-01-31
The centromere is one of the most important chromosomal elements. It is required for proper chromosome segregation in mitosis and meiosis and readily recognizable as the primary constriction of mitotic chromosomes. Proper centromere function is essential to ensure genome stab...
Programme: FP7-IDEAS-ERC
Record Number: 106164
Last updated on: 2017-08-22
Fitness drivers in long-distance migrants: the interacting roles of physiology, social biology, ecological and physical environments
ID: 310820
Start date: 2013-02-01, End date: 2019-01-31
Long distance migration in birds is among the most dramatic and exciting phenomena in nature. However despite many years of study, there are still huge gaps in our understanding of how this behaviour shapes individual ecology and influences population processes. For example, ...
Programme: FP7-IDEAS-ERC
Record Number: 106595
Last updated on: 2017-06-26
SUMOrice: Exploiting an emerging protein modification system, SUMOylation to boost rice yield during drought and salt stress
ID: 310235
Start date: 2013-04-01, End date: 2019-03-31
"To feed 9 billion people by 2050 is an unprecedented challenge. Rice is the food source for the majority of the world's population but also a model for cereals. Drought and related high salinity during essential periods of plant growth affects nearly all crops including the ...
Programme: FP7-IDEAS-ERC
Record Number: 107495
Last updated on: 2017-06-21
Biochemical reconstitution of DNA repair reactions on physiological chromatin substrates
ID: 311336
Start date: 2013-01-01, End date: 2018-12-31
For cells and organisms to survive and propagate, they must accurately pass on their genetic information to the next generation. Errors in this process may arise from spontaneous mistakes in normal cellular metabolism, or from exposure to external agents, such as chemical mut...
Programme: FP7-IDEAS-ERC
Record Number: 105906
Last updated on: 2017-06-05
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List retrieved on: 2017-11-21
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