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Genomics of adaptive divergence in Fungi
ID: 309403
Start date: 2013-03-01, End date: 2018-02-28
Understanding the genetic and genomic processes behind adaptive phenotypes remains a holy grail in biology. Fungi are poorly studied regarding these processes, despite their great tractability as model eukaryote organisms and their medical, industrial, and ecological importan...
Programme: FP7-IDEAS-ERC
Record Number: 107359
Last updated on: 2017-04-10
Factor XII and the contact system: 
cross-talk between thrombosis and inflammation
ID: 311575
Start date: 2013-08-01, End date: 2018-07-31
Combinations of proinflammatory and procoagulant reactions are the unifying principle for a variety of disorders affecting the cardiovascular system. Factor XII (FXII, Hageman factor) is a plasma protease that initiates the contact system. This system starts a cascade of proc...
Programme: FP7-IDEAS-ERC
Record Number: 109422
Last updated on: 2017-03-27
Laser: driving force for a new generation of hearing aids
ID: 311469
Start date: 2012-10-01, End date: 2018-05-31
This proposal presents an unconventional method for the stimulation of the outer and middle ear that may change the current concept of hearing aids. Photons of the visible light are known to activate the visual sensory cells through photoreceptors. However, when the so-called...
Programme: FP7-IDEAS-ERC
Record Number: 105124
Last updated on: 2017-03-27
Next generation sequencing for detection of human primary immunodeficiency syndromes characterized by impaired cytotoxic lymphocyte function
ID: 311335
Start date: 2013-05-01, End date: 2018-04-30
Human primary immunodeficiencies affecting cytotoxic lymphocyte function are associated with high morbidity and mortality. They often present as hyperinflammatory syndromes triggered by viral infections, hematological malignancies, or systemic autoimmunity. Although recent ad...
Programme: FP7-IDEAS-ERC
Record Number: 108234
Last updated on: 2017-03-27
Towards evidence-based genomic medicine: filling the evidence gaps through modelling studies
ID: 310884
Start date: 2014-01-01, End date: 2018-12-31
At increasingly high rate, genome-wide association and whole genome sequencing studies unravel genetic variants implicated in common diseases such as coronary heart disease, cancer, dementia and type 2 diabetes. One of the major promises is that these advances will lead to mo...
Programme: FP7-IDEAS-ERC
Record Number: 111046
Last updated on: 2017-03-13
Bacterial Cell Morphogenesis
[PROJECT] BACEMO - Bacterial Cell Morphogenesis
ID: 311231
Start date: 2013-02-01, End date: 2018-01-31
In bacteria, the though external cell wall and the intracellular actin-like (MreB) cytoskeleton are major determinants of cell shape. The biosynthetic pathways and chemical composition of the cell wall, a three dimensional polymer network that is one of the most prominent tar...
Programme: FP7-IDEAS-ERC
Record Number: 105022
Last updated on: 2017-03-06
Customized Micro Total Analysis Systems to Study Human Phase I Metabolism
ID: 311705
Start date: 2013-05-01, End date: 2019-02-28
The goal of this project is to develop inexpensive, high-throughput technology to screen the thus far unexplored metabolic interactions between environmental and household chemicals and clinically relevant drugs. The main influential focus will be on human phase I metabolism ...
Programme: FP7-IDEAS-ERC
Record Number: 106984
Last updated on: 2017-02-27
small RNA mediated heterochromatin formation in fission yeast
ID: 309584
Start date: 2012-11-01, End date: 2018-10-31
Regulation of genome expression is essential for cell proliferation, differentiation, development and viability. Small RNA silencing pathways are involved in the cellular control of gene expression and in protection of the genome against mobile repetitive DNA sequences, retro...
Programme: FP7-IDEAS-ERC
Record Number: 105256
Last updated on: 2016-12-19
Biogenesis of lipid droplets and lipid homeostasis
ID: 309477
Start date: 2013-02-01, End date: 2018-01-31
Organisms and cells face a myriad of environmental changes with periods of nutrient surplus and shortage. It is therefore not surprising that in all kingdoms of life, cells have evolved the means to store energy and thereby minimize the effects of environmental fluctuations. ...
Programme: FP7-IDEAS-ERC
Record Number: 105402
Last updated on: 2016-12-19
Full biomechanical characterization of the coronary atherosclerotic plaque: biomechanics meets imaging
ID: 310457
Start date: 2013-05-01, End date: 2019-04-30
Myocardial infarction is responsible for nearly 40% of the mortality in the western world and is mainly triggered by rupture of vulnerable atherosclerotic plaques in the coronary arteries. Biomechanical parameters play a major role in the generation and rupture of vulnerable ...
Programme: FP7-IDEAS-ERC
Record Number: 107424
Last updated on: 2016-12-12
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List retrieved on: 2017-11-21
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