Community Research and Development Information Service - CORDIS

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Order in Disorder: Context-dependent strategies for integrating peptide-mediated interactions
ID: 310873
Start date: 2012-12-01, End date: 2017-11-30
Peptide-mediated protein interactions are emerging as key regulators of many important regulatory processes in the cell. Short motifs, usually embedded into disordered regions of the protein, interact with specific sets of protein partners in a transient way and allow efficie...
Programme: FP7-IDEAS-ERC
Record Number: 105647
Last updated on: 2016-08-29
‘Seeing’ with the ears, hands and bionic eyes: from theories about brain organization to visual rehabilitation
ID: 310809
Start date: 2013-09-01, End date: 2018-08-31
My lab's work ranges from basic science, querying brain plasticity and sensory integration, to technological developments, allowing the blind to be more independent and even “see” using sounds and touch similar to bats and dolphins (a.k.a. Sensory Substitution Devices, SSDs),...
Programme: FP7-IDEAS-ERC
Record Number: 109040
Last updated on: 2016-08-29
The analysis of mitochondrial dynamics in ageing and neurodegeneration
ID: 309742
Start date: 2013-01-01, End date: 2018-12-31
The survival of our most active tissues, such as the brain and heart, throughout decades of a human lifespan presents an extraordinary biological challenge. Mitochondria are central to the life and death of these tissues. They provide the cellular energy required by these cel...
Programme: FP7-IDEAS-ERC
Record Number: 105785
Last updated on: 2016-08-29
Environmentally-induced Developmental Origins of Health and Disease
ID: 311765
Start date: 2013-02-01, End date: 2018-01-31
The DOHaD (Developmental Origins of Health and Disease) hypothesis states that, because of developmental plasticity, in utero and early postnatal stressors can increase chronic disease risk in childhood and later. Alterations of epigenetic marks, impacting on gene expression,...
Programme: FP7-IDEAS-ERC
Record Number: 106798
Last updated on: 2016-08-19
Role of endoplasmic reticulum in neurodegeneration: physiopathology of a form of hereditary spastic paraplegia as a model
ID: 311149
Start date: 2013-04-01, End date: 2018-03-31
Endoplasmic reticulum (ER) is a dynamic, tubular intracellular network implicated in a variety of cellular functions. Although it is known to play a role in neurodegeneration, its organization and precise function in neurons have been neglected. I will use the physiopathology...
Programme: FP7-IDEAS-ERC
Record Number: 107496
Last updated on: 2016-08-15
Counteracting psychosis by optimizing interaction
ID: 309767
Start date: 2013-04-01, End date: 2018-03-31
Psychotic disorders are amongst the most severe mental disorders. However, current treatments have failed to reduce disability or change the prospects for recovery for patients with a psychotic disorder. In this project, I will investigate an entirely novel therapy, targeting...
Programme: FP7-IDEAS-ERC
Record Number: 107974
Last updated on: 2016-08-15
Autophagy as a cancer treatment
[PROJECT] CANCERPHAGY - Autophagy as a cancer treatment
ID: 311331
Start date: 2012-10-01, End date: 2018-09-30
Cancer is one of the most prevalent human killer diseases. Autophagy, a lysosome-mediated process that degrades cellular components and damaged organelles, has recently emerged as an important player in cancer. Indeed, autophagy inhibition promotes cancer initiation through g...
Programme: FP7-IDEAS-ERC
Record Number: 104727
Last updated on: 2016-08-01
Memory B cell immunity in chronic viral infection
ID: 310962
Start date: 2013-09-01, End date: 2018-08-31
This project aims for a quantum leap in the understudied area of memory B cell immunity to chronic viral infection. It provides i) a landscape analysis of primary and memory B cell responses to chronic viral challenge, ii) investigates receptor hypermutation of memory B cells...
Programme: FP7-IDEAS-ERC
Record Number: 106703
Last updated on: 2016-07-25
Ancient Pathogen Genomics of Re-Emerging Infectious Disease
ID: 310920
Start date: 2013-01-01, End date: 2017-12-31
Here we propose a first step toward a direct reconstruction of the evolutionary history of human infectious disease agents by obtaining genome wide data of historic pathogens. Through an extensive screening of skeletal collections from well-characterized catastrophe, or emerg...
Programme: FP7-IDEAS-ERC
Record Number: 104863
Last updated on: 2016-07-18
Mechanisms that prevent aneuploidy
[PROJECT] NOANEUPLOIDY - Mechanisms that prevent aneuploidy
ID: 311358
Start date: 2013-01-01, End date: 2017-12-31
The mechanisms that safeguard cells against aneuploidy are of great interest as aneuploidy contributes to tumorigenesis. To gain insight into these mechanisms, I studied the behavior of cells entering mitosis with damaged chromosomes. I used the endonuclease I-CreI to generat...
Programme: FP7-IDEAS-ERC
Record Number: 106458
Last updated on: 2016-07-08
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List retrieved on: 2017-11-23
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