Community Research and Development Information Service - CORDIS

Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Cardiac myosin light chain kinase function in human pluripotent stem cell derived cardiomyocytes
ID: 276186
Start date: 2012-09-14, End date: 2016-12-31
The main hurdle to the effective use of stem cell derived cardiomyocytes (hESC-CMs and hIPSC-CMs) in drug toxicology screening and transplantation therapy is their embryonic nature. It is recognised that hESC-CM and hIPSC-CM are immature and undergo limited maturation in the ...
Programme: FP7-PEOPLE
Record Number: 100928
Last updated on: 2017-09-24
Measurement of the global characteristics of Relativistic Heavy Ion Collisions with the ATLAS detector at LHC
ID: 231033
Start date: 2008-11-01, End date: 2012-10-31
The Large Hadron Collider (LHC) soon to be commissioned at CERN opens a new energy frontier and a new era of quantitative understanding of the phase transition between hadronic nuclear matter and the Quark-Gluon Plasma. The primary and initial question for the relativistic he...
Programme: FP7-PEOPLE
Record Number: 88943
Last updated on: 2017-05-30
The Effect of On-Line Product Search on the Market Structure of Consumer Durables
ID: 230962
Start date: 2008-09-01, End date: 2012-08-31
"We propose to study the working of markets when consumers do not want to search all available choice options and when sellers recommend products based on what ""similar consumers"" have bought in the past. We argue that the current practice of on-line selling offers signific...
Programme: FP7-PEOPLE
Record Number: 88786
Last updated on: 2017-05-30
ER Stress and Photoreceptor Degeneration in Drosophila
ID: 230935
Start date: 2008-12-01, End date: 2014-04-01
The endoplasmic reticulum (ER) is the cell organelle where secretory and membrane proteins are synthesized and folded. The presence of unfolded/misfolded proteins in the ER causes stress to the cell (“ER stress”) and activates the Unfolded Protein Response (UPR), a cellular r...
Programme: FP7-PEOPLE
Record Number: 88941
Last updated on: 2017-05-30
Study and modification of T-cell receptor structure to enhance anti-tumor activity
ID: 224851
Start date: 2008-10-01, End date: 2012-09-30
Adoptive cell transfer of tumor-reactive lymphocytes has been shown to mediate the regression of large solid tumors in cancer patients. To overcome the need to isolate and expand tumor-reactive lymphocytes that pre-exist in the patient, it is possible to engineer cells to exp...
Programme: FP7-PEOPLE
Record Number: 88757
Last updated on: 2017-05-30
Radio pulsars with LOFAR: a study of extreme physics laboratories
ID: 224838
Start date: 2008-05-01, End date: 2012-04-30
A radio pulsar is formed when the iron core of a massive star collapses in a supernova explosion. Due to their extreme compactness and supernuclear density radio pulsars are extremely stable rotators. Our goal is 1) to use radio pulsars to improve our limited understanding of...
Programme: FP7-PEOPLE
Record Number: 88754
Last updated on: 2017-05-30
Microtubule organizing centers and microtubule nucleation in mitosis
ID: 224835
Start date: 2008-07-21, End date: 2012-07-20
Centrosomes are multifunctional organelles crucial for a large number of cellular functions including the organization of microtubules. In mitosis centrosomes contribute to assembly, orientation and function of the mitotic spindle, which is important for proper segregation of...
Programme: FP7-PEOPLE
Record Number: 88753
Last updated on: 2017-05-30
Stem Cells and Cancer Stem Cells in Mouse Mammary Glands
ID: 224821
Start date: 2009-05-25, End date: 2013-05-24
It is thought that, although cancer stem cells are a small minority in the tumor cell population, they can escape the toxicity of drugs used for treatment, as they are relatively quiescent, i.e. chemotherapy can lead effectively to remission, but not frequently to a cure. An ...
Programme: FP7-PEOPLE
Record Number: 91100
Last updated on: 2017-05-30
Dissecting the molecular mechanisms of protein glycosylation and glycoprotein trafficking in cereal endosperm
ID: 224806
Plant-derived pharmaceuticals (PDPs) have immense potential to address the economic and capacity limitations of current fermenter-based production technology. Several complex multi-subunit and glycosylated proteins have been produced in transgenic plants, which are safe, conv...
Programme: FP7-PEOPLE
Record Number: 192738
Last updated on: 2017-05-30
Structural characterization of filamentous bacteriophage viruses by magic-angle spinning solid-state NMR spectroscopy
ID: 224800
Start date: 2008-03-01, End date: 2012-02-29
Filamentous bacteriophages comprise a family of viruses that share a similar virion structure and life cycle. The virion is composed of a circular ssDNA wrapped by thousands of similar copies of a major coat protein and several different minor coat proteins in both ends. Due ...
Programme: FP7-PEOPLE
Record Number: 86448
Last updated on: 2017-05-30
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List retrieved on: 2017-11-20
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