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Reach  α-synuclein-dependent neurodegeneration: clinical development of therapeutic AFFITOPE vaccines for Parkinson’s disease and multisystem atrophy
ID: 602999
Start date: 2013-10-01, End date: 2017-09-30
The goal of SYMPATH is to advance clinical development of therapeutic vaccines targeting α-synuclein (aSyn)-driven neurodegenerative diseases (ND). It addresses Parkinson’s disease (PD) and multiple system atrophy (MSA), two synucleopathies, for which no causal therapy exists...
Programme: FP7-HEALTH
Record Number: 109923
Last updated on: 2017-09-10
Towards Early diagnosis and biomarker validation in Arthritis Management
ID: 305549
Start date: 2012-11-01, End date: 2016-10-31
An ideal intervention in a chronic inflammatory disease such as Rheumatoid Arthritis (RA) would be a preventive one. In order to develop preventive strategies and therapies two key developments need to occur: (1) Biomarkers need to be identified that can be used to predict an...
Programme: FP7-HEALTH
Record Number: 105516
Last updated on: 2017-09-10
Lipid droplets as dynamic organelles of fat deposition and release: Translational research towards human disease
ID: 202272
Start date: 2008-05-01, End date: 2012-10-31
Lipids are central to the regulation and control of cellular processes by acting as basic building units for biomembranes, the platforms for the vast majority of cellular functions. Recent developments in lipid mass spectrometry have set the scene for a completely new way to ...
Programme: FP7-HEALTH
Record Number: 88230
Last updated on: 2017-09-10
Long-term, prospective study evaluating clinical and molecular biomarkers of epileptogenesis in a genetic  model of epilepsy – tuberous sclerosis complex
ID: 602391
Start date: 2013-11-01, End date: 2018-10-31
Despite a great progress in the management of epilepsy, still one third of patients is refractory to available medications. The incidence of epilepsy is highest in infancy and 50% of children experience epilepsy-related comorbidities, such as developmental delay and autism. T...
Programme: FP7-HEALTH
Record Number: 110144
Last updated on: 2017-09-03
International study for treatment of childhood relapsed ALL 2010 with standard therapy, systematic integration of new agents, and establishment of standardized diagnostic and research
ID: 278514
Start date: 2011-10-01, End date: 2017-09-30
Though survival of children with acute lymphoblastic leukaemia (ALL) has improved, relapse remains a leading cause of mortality in childhood cancer. Given the rarity of the disease, only a large international cooperative group can recruit sufficient patients for prospective s...
Programme: FP7-HEALTH
Record Number: 102104
Last updated on: 2017-09-03
Novel approaches for prevention and degeneration of pathogenic bacteria biofilms formed on medical devices e.g. catheters
ID: 278402
Start date: 2012-01-01, End date: 2014-12-31
Biofilms are bacterial communities encased in a self-produced hydrated polymeric matrix. An important characteristic of microbial biofilms is their innate resistance to the immune system and susceptibility to antibiotics. This resistance has made microbial biofilms a common c...
Programme: FP7-HEALTH
Record Number: 101792
Last updated on: 2017-09-03
European ResearcH on DevElopmentAL, BirtH and Genetic Determinants of Ageing
ID: 277849
Start date: 2012-02-01, End date: 2015-01-31
Developmental plasticity modulated by epigenetic processes such as methylation and post-translational modifications is influenced by early life events and determines risk of age related diseases later in life We propose a multi-disciplinary approach incorporating biochemistry...
Programme: FP7-HEALTH
Record Number: 101782
Last updated on: 2017-09-03
ERA-Net on Rare Diseases
[PROJECT] E-RARE-2 - ERA-Net on Rare Diseases
ID: 266608
Start date: 2010-10-01, End date: 2014-11-30
Rare diseases represent an important public-health issue, affecting 26-30 million persons across Europe, and a major challenge for research. The fragmentation of resources and knowledge for the 6000-8000 rare diseases and the lack of treatment for the majority of them necessi...
Programme: FP7-HEALTH
Record Number: 97885
Last updated on: 2017-09-03
ERA-NET on Translational Cancer Research
ID: 266559
Start date: 2011-01-01, End date: 2014-12-31
Cancer is a worldwide health burden and a major public health challenge in Europe, responsible for 25% of all deaths; a situation expected to worsen with population ageing. The strengthening of translational cancer research is an urgent need in European cancer research, i.e. ...
Programme: FP7-HEALTH
Record Number: 97674
Last updated on: 2017-09-03
Randomised controlled trial to evaluate electronic Symptom Management using the Advanced Symptom Management System (ASyMS) Remote Technology for patients with cancers
ID: 602289
Start date: 2014-02-01, End date: 2019-01-31
The eSMART programme of work will demonstrate the effects of a real-time, mobile phone based, remote patient monitoring intervention on key patient outcomes and delivery of care provided to people with cancer during and after chemotherapy. Utilising the remote patient monitor...
Programme: FP7-HEALTH
Record Number: 109341
Last updated on: 2017-08-27
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List retrieved on: 2017-09-22
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