Community Research and Development Information Service - CORDIS

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Therapeutic TriMix / mRNA based Vaccine in Chronic HIV-1 Infected Patients Receiving Antiretroviral Therapy
ID: 602570
Start date: 2013-12-01, End date: 2017-11-30
To find a therapy alternative to cART for life is one of the hot topics of investigation in HIV field. Therapeutic vaccination seems to be the best option. We have reported in a double-blind placebo controlled study some of the best, most solid data showing that HIV-1 specifi...
Programme: FP7-HEALTH
Record Number: 110278
Last updated on: 2017-06-21
HEPATIC MICROFLUIDIC BIOREACTOR
[PROJECT] HEMIBIO - HEPATIC MICROFLUIDIC BIOREACTOR
ID: 266777
Start date: 2011-01-01, End date: 2015-12-31
The goal of HeMiBio is to develop a hepatic microfluidic bioreactor from human iPSC-derived hepatocytes, hepatic sinusoidal endothelial cells (HSEC) and stellate cells (HSC), suitable for inclusion in a repeated dose toxicity testing strategy of pharmaceuticals/cosmetic ingre...
Programme: FP7-HEALTH
Record Number: 105662
Last updated on: 2017-06-12
Stem Cells for Relevant Efficient Extended and Normalized Toxicology
ID: 266753
Start date: 2011-01-01, End date: 2015-12-31
In the development of products for use by humans it is vital to identify compounds with toxic properties at an early stage of their development, to avoid spending time and resource on unsuitable and potentially unsafe candidate products. Human pluripotent stem cell lines offe...
Programme: FP7-HEALTH
Record Number: 97710
Last updated on: 2017-06-12
Effective Perinatal Intensive Care in Europe: translating knowledge into evidence based practice
ID: 259882
Start date: 2011-01-01, End date: 2015-12-31
Context: Very preterm infants face high risks of mortality and long-term neuro-developmental impairment. Rates of mortality and morbidity vary by a factor greater than two between European regions. This project’s overriding aim is to improve these infants’ survival and long-t...
Programme: FP7-HEALTH
Record Number: 97698
Last updated on: 2017-06-12
Identification and development of vaccine candidates for Buruli Ulcer Disease
ID: 241500
Start date: 2010-03-01, End date: 2013-05-31
Buruli ulcer disease (BUD), caused by Mycobacterium ulcerans, is a neglected bacterial infection of the poor in remote rural areas, mostly affecting children. BUD, the third most common mycobacterial disease in immunocompetent humans after tuberculosis and leprosy, is most en...
Programme: FP7-HEALTH
Record Number: 94059
Last updated on: 2017-06-12
Evaluation of antibiotics (ciprofloxacin and fluconazole) for the treatment of infections in preterm and term neonates
ID: 223614
Start date: 2008-11-01, End date: 2015-10-31
The aim of TINN is to evaluate ciprofloxacin, fluconazole and micafungin in neonates; two anti-infectious drugs included in the EMEA priority list of the therapeutic areas that need specific drug evaluation in preterm and term neonates. These drugs are prescribed off-label to...
Programme: FP7-HEALTH
Record Number: 89361
Last updated on: 2017-06-12
Use of innovative strategies for beta-cell imaging in diabetes mellitus
ID: 222980
Start date: 2008-10-01, End date: 2013-03-31
The development of sensitive, non-invasive methods for the characterisation and quantification of beta-cell mass would greatly enhance our means for gaining understanding of the pathophysiology of diabetes and allow the development of novel therapies to prevent, halt and reve...
Programme: FP7-HEALTH
Record Number: 88826
Last updated on: 2017-06-12
Early diagnosis, treatment and prevention of mood disorders targetting the activated inflammatory response system
ID: 222963
Start date: 2008-11-01, End date: 2013-04-30
Partners come from 10 European countries to achieve two main objectives: A) The further exploration of 3 animal models (the OBX rat, GS rat and NOD mouse) characterized by an activated immune response system (IRS), an abnormal tryptophan catabolism and a depressive-like behav...
Programme: FP7-HEALTH
Record Number: 89344
Last updated on: 2017-06-12
Social Innovations Promoting Active and Healthy Ageing
ID: 306058
Start date: 2012-12-01, End date: 2015-11-30
INNOVAGE is an ambitious project is dedicated to developing and testing, as well as surveying and cataloguing, social innovations that will have a solid impact on improving the quality of life and well-being of older people. In particular the project aims to make a major cont...
Programme: FP7-HEALTH
Record Number: 105830
Last updated on: 2017-06-05
To decipher the optimal management of systemic sclerosis
ID: 305495
Start date: 2012-12-01, End date: 2015-11-30
The current approach to diagnosis and management of the rare disease systemic sclerosis (SSc) is based on American College of Rheumatology criteria with low sensitivity and few validated recommendations for the therapy of the disease and its manifold organ manifestations. To ...
Programme: FP7-HEALTH
Record Number: 106189
Last updated on: 2017-06-05
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List retrieved on: 2017-06-23