Community Research and Development Information Service - CORDIS

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Mechanisms and Treatment of Migraine and its Chronification
ID: 602633
Start date: 2014-02-01, End date: 2017-01-31
Migraine is a common brain disorder, typically characterised by recurring, incapacitating attacks of 1-3 days of severe headache, autonomic dysfunction, and sometimes aura symptoms. The disease affects 15% of all European citizens including children, ranks among the WHO top 1...
Programme: FP7-HEALTH
Record Number: 109470
Last updated on: 2017-10-06
King of hearts, joints and lungs; periodontal pathogens as etiologic factor in RA, CVD and COPD and their impact on treatment strategies
ID: 306029
Start date: 2013-04-01, End date: 2017-03-31
Extensive clinical and epidemiological data clearly shows that chronic periodontal disease (PD), the most prevalent infectious inflammatory disease of mankind, is strongly linked to systemic inflammatory diseases such as cardiovascular diseases (CVD) , rheumatoid arthritis (R...
Programme: FP7-HEALTH
Record Number: 106057
Last updated on: 2017-10-06
Human stem cell applications for the treatment of hearing loss
ID: 603029
Start date: 2013-11-01, End date: 2017-10-31
Hearing impairment is the most frequent human sensory deficit and is mainly caused by the irreversible loss of neurosensory cells in the cochlea. The lack of human otic cell models represents a significant roadblock that has hampered the development of drug-based or cell-base...
Programme: FP7-HEALTH
Record Number: 110640
Last updated on: 2017-09-24
Neurobiology and Treatment of Adolescent Female Conduct Disorder: The Central Role of Emotion Processing
ID: 602407
Start date: 2013-09-01, End date: 2018-02-28
Conduct Disorder (CD) and Oppositional Defiant Disorder with symptoms of Conduct Disorder (which is included among the abbreviation “CD” throughout the proposal) has a highly negative impact for the affected individual as well as for families and society. Although the number ...
Programme: FP7-HEALTH
Record Number: 110199
Last updated on: 2017-09-24
European stem cell consortium for neural cell replacement, reprogramming and functional brain repair
ID: 602278
Start date: 2013-10-01, End date: 2017-09-30
Neurostemcellrepair aims at taking human stem cells through the final steps toward clinical application in cell replacement therapy for neurological disorders. PD will be taken as the prototypical disease because stem cell therapy is now close to clinical translation. Moreove...
Programme: FP7-HEALTH
Record Number: 110638
Last updated on: 2017-09-24
Human pluripotent stem cell differentiation, safety and preparation for therapeutic transplantation in Huntington’s disease
ID: 602245
Start date: 2013-10-01, End date: 2018-03-31
This project will tackle the huge complexity of taking stem cell therapies to clinical application for neurodegenerative disease by focusing on selective differentiation of a single neuronal phenotype (medium spiny striatal neuron: MSN) for a single well-defined disease (Hunt...
Programme: FP7-HEALTH
Record Number: 109572
Last updated on: 2017-09-24
Development and clinical trials of a new Software ENgine for the Assessment & Optimization of drug and non-drug Therapy in Older peRsons
ID: 305930
Start date: 2012-10-01, End date: 2018-06-30
The European population of older people with multiple chronic diseases (multimorbidity) is increasing steadily in tandem with the rising population of people aged ≥ 65 years. Older multimorbid people are at high risk of polypharmacy (PP), inappropriate prescribing (IP), adver...
Programme: FP7-HEALTH
Record Number: 105397
Last updated on: 2017-09-24
Stem-cell based therapy for kidney repair
ID: 305436
Start date: 2012-11-01, End date: 2017-10-31
Chronic kidney disease (CKD) affects 8% of the European population and ultimately results in renal failure due to progressive fibrosis. CDK carries a high mortality risk and the number of affected people rises, increasing the demand on renal replacement therapies while the nu...
Programme: FP7-HEALTH
Record Number: 105515
Last updated on: 2017-09-24
Reach  α-synuclein-dependent neurodegeneration: clinical development of therapeutic AFFITOPE vaccines for Parkinson’s disease and multisystem atrophy
ID: 602999
Start date: 2013-10-01, End date: 2017-09-30
The goal of SYMPATH is to advance clinical development of therapeutic vaccines targeting α-synuclein (aSyn)-driven neurodegenerative diseases (ND). It addresses Parkinson’s disease (PD) and multiple system atrophy (MSA), two synucleopathies, for which no causal therapy exists...
Programme: FP7-HEALTH
Record Number: 109923
Last updated on: 2017-09-10
Novel antifungals to treat resistant organisms
ID: 601963
Start date: 2013-07-01, End date: 2016-06-30
Invasive fungal diseases are estimated to kill 1.5 million people each year. The incidence of mortality has risen significantly across the EU over the last 20 years due to an expansion of at risk patient populations. Given the obvious importance of these diseases it is perhap...
Programme: FP7-HEALTH
Record Number: 108714
Last updated on: 2017-09-10
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List retrieved on: 2017-10-18
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