Community Research and Development Information Service - CORDIS

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Rational Therapy for Breast Cancer: Individualized Treatment for Difficult-to-Treat Breast Cancer Subtypes
ID: 258967
Start date: 2011-01-01, End date: 2018-06-30
Cancer genotyping has identified a number of correlations between mutations in specific genes and responses to targeted anti-cancer drugs, with many mutations occurring in kinases or downstream signaling components. While there are several ongoing large-scale genome re-sequen...
Programme: FP7-HEALTH
Record Number: 97660
Last updated on: 2017-07-16
Metformin for treatment of polycystic ovary syndrome in children
ID: 602243
Start date: 2013-10-01, End date: 2017-03-31
PCOS, a common disorder affecting 5-10% of women of reproductive age is characterized by cystic ovarian morphology, androgen excess, and/or irregular periods and emerges during or shortly after puberty. The common off-label use of metformin for treating PCOS in children appea...
Programme: FP7-HEALTH
Record Number: 110171
Last updated on: 2017-07-12
Clinical Development of Nitisinone for Alkaptonuria
ID: 304985
Start date: 2012-11-01, End date: 2018-04-30
DevelopAKUre is a proposal to fund the clinical development of an orphan designated drug, nitisinone, for the treatment of a rare Mendelian disease, Alkaptonuria (AKU). AKU is a genetic deficiency of homogentisic acid dioxygenase, causing high levels of homogentisic acid (HGA...
Programme: FP7-HEALTH
Record Number: 106157
Last updated on: 2017-07-12
VitaminD3-Omega3-Home Exercise- HeALTHy Ageing and Longevity Trial
ID: 278588
Start date: 2012-01-01, End date: 2018-06-30
As the European population is ageing rapidly, the growing number of seniors with age-related chronic diseases poses a challenge on European societies and health care systems. Therapeutic interventions that are effective, affordable and well-tolerated in the prevention of chro...
Programme: FP7-HEALTH
Record Number: 103473
Last updated on: 2017-07-12
The European Network for Translational Research in Atrial Fibrillation
ID: 261057
Start date: 2010-11-01, End date: 2015-10-31
The initiation and perpetuation of atrial fibrillation (AF) can be regarded as a complication of a progressive transformation of the structure and functional properties of the atria. This transformation is the result of complex and multiple changes at the molecular, cellular ...
Programme: FP7-HEALTH
Record Number: 96749
Last updated on: 2017-07-12
Integrated research on DEvelopmental determinants of Aging and Longevity
ID: 259679
Start date: 2011-02-01, End date: 2016-01-31
IDEAL will obtain insight into the role of early life conditions affecting late-life health, disease and aging, and the role of epigenetic regulation therein. IDEAL will identify the determinants and targets of this epigenetic regulation utilizing a resource of unique human c...
Programme: FP7-HEALTH
Record Number: 98424
Last updated on: 2017-07-12
Metastatic tumours facilitated by hypoxic tumour micro-environments
ID: 222741
Start date: 2009-02-01, End date: 2014-07-31
Recent research suggests that the hypoxic micro-environment of tumours is one of the major drivers of metastatic spread of cancer. Furthermore, hypoxic tumour micro-environments may result in treatment resistance of cancer cells, therefore causing a double effect of reducing ...
Programme: FP7-HEALTH
Record Number: 91061
Last updated on: 2017-07-12
Personalized diagnosis and treatment of hyperinsulinemic hypoglycaemia caused by beta-cell pathology
ID: 602812
Start date: 2014-04-01, End date: 2018-03-31
Background: Hyperinsulinaemic hypoglycaemia (HH) is a potentially lethal disease caused by over functioning beta cells derived from the pancreatic islets of Langerhans. Lethal HH and brain damage is a problem especially in infants with congenital HH. Current therapeutic appro...
Programme: FP7-HEALTH
Record Number: 185455
Last updated on: 2017-07-02
Vaccination against Shigella and ETEC: novel antigens, novel approaches
ID: 261472
Start date: 2010-11-01, End date: 2017-12-31
To contribute to the development of vaccines against Shigella and ETEC for children of the developing world, STOPENTERICS will provide novel solutions by imposing a two-fold paradigm switch: (i) to break the dogma of serotype-specificity by inducing a cross-protective immunit...
Programme: FP7-HEALTH
Record Number: 97173
Last updated on: 2017-07-02
Alcohol Measures for Public Health Research Alliance (AMPHORA)
ID: 223059
Start date: 2009-01-01, End date: 2012-12-31
AMPHORA is a Europe wide project involving researches and research institutions from 14 European countries, and counterparts and organizations from all 27 Member States, that will provide new scientific evidence for the best public health measures to reduce the harm done by a...
Programme: FP7-HEALTH
Record Number: 92876
Last updated on: 2017-06-28
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List retrieved on: 2017-07-23
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