Community Research and Development Information Service - CORDIS

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Human pluripotent stem cell differentiation, safety and preparation for therapeutic transplantation in Huntington’s disease
ID: 602245
Start date: 2013-10-01, End date: 2018-03-31
This project will tackle the huge complexity of taking stem cell therapies to clinical application for neurodegenerative disease by focusing on selective differentiation of a single neuronal phenotype (medium spiny striatal neuron: MSN) for a single well-defined disease (Hunt...
Programme: FP7-HEALTH
Record Number: 109572
Last updated on: 2017-12-11
Taking imaging into the therapeutic domain: Self-regulation of brain systems for mental disorders
ID: 602186
Start date: 2013-11-01, End date: 2018-10-31
Our proposal is based on the idea that real-time functional neuroimaging can be used to train patients to regulate their own brain activity via neurofeedback training and thus modulate the brain networks of mental disorder, restore function, improve symptoms and promote resil...
Programme: FP7-HEALTH
Record Number: 109338
Last updated on: 2017-12-11
comBinig cELLular and humoral immunE RespOnses as a vaccine strategy against staPHhylOcoccus aureus pathogeN
ID: 601783
Start date: 2013-09-01, End date: 2016-08-31
Staphylococcus aureus, including Meticillin-resistant S. aureus (MRSA), is one of the most important bacterial pathogens, causing skin, wound, and deep infections in both the community and in hospitals. Treatment is difficult and expensive and may require prolonged intravenou...
Programme: FP7-HEALTH
Record Number: 108686
Last updated on: 2017-12-11
Bringing Regenerative Medicine into the market: Allogeneic eASCs Phase IB/IIA clinical trial for treating Rheumatoid Arthritis
ID: 279174
Start date: 2012-01-01, End date: 2014-12-31
Treating Rheumatoid Arthritis (RA) is a crucial challenge for the health systems. RA is the most common inflammatory arthritis, affecting 0.5% to 1% of the general population worldwide with little variation of the prevalence among countries. The current pharmacological manage...
Programme: FP7-HEALTH
Record Number: 102108
Last updated on: 2017-12-11
A novel generation of skin substitutes to clinically treat a broad spectrum of severe skin defects
ID: 279024
Start date: 2011-10-01, End date: 2016-09-30
Large full-thickness skin defects resulting from burns, soft tissue trauma, congenital giant nevi, tumour resection, and disease leading to skin necrosis, represent a significant and common clinical problem worldwide. This problem is far from being solved. The main challenge ...
Programme: FP7-HEALTH
Record Number: 101996
Last updated on: 2017-12-11
High-throughput peptidomics and transcriptomics of animal venoms for discovery of novel therapeutic peptides and innovative drug development
ID: 278346
Start date: 2011-11-01, End date: 2015-10-31
Animal venoms are complex cocktails of peptides that have enormous potential as novel therapeutic leads. Replicating in vitro the diversity of venoms by generating large synthetic combinatorial peptide libraries will solve the challenge of working with limited amounts of natu...
Programme: FP7-HEALTH
Record Number: 101790
Last updated on: 2017-12-11
Oral Off-patent Oncology Drugs for Kids
ID: 223158
Start date: 2008-09-01, End date: 2011-08-31
There is an urgent need for appropriate oral formulations of anticancer drugs for the treatment of paediatric malignancies in children. The goal of the O3K consortium is to develop oral liquid formulations of Cyclophosphamide and Temozolomide, important chemotherapeutics whic...
Programme: FP7-HEALTH
Record Number: 91037
Last updated on: 2017-12-11
Observational Prolonged Trial In Myotonic dystrophy type 1 to Improve QoL-Standards, a Target Identification Collaboration
ID: 305697
Start date: 2012-11-01, End date: 2017-04-30
OPTIMISTIC is a proposal for a European collaborative project of doctors, scientists, relevant stakeholders (TREAT-NMD, patient organizations) and SMEs with the aim to improve clinical practice for patients suffering from a rare, inherited, and neglected disease, myotonic dys...
Programme: FP7-HEALTH
Record Number: 106243
Last updated on: 2017-12-07
Beta cell preservation via antigen-specific immunotherapy in Type 1 Diabetes: Enhanced Epidermal Antigen Delivery Systems
ID: 305305
Start date: 2012-09-01, End date: 2017-05-31
Current approaches to improving glycaemic control in type 1 diabetes are centered on increasingly complex insulin delivery systems. However, less than 30% of patients can achieve target levels of glucose control with this approach even in a clinical trial setting and many pat...
Programme: FP7-HEALTH
Record Number: 105252
Last updated on: 2017-12-07
The effect of intracoronary reinfusion of bone marrow-derived mononuclear cells (BM-MNC) on all-cause mortality  in acute myocardial infarction
ID: 278967
Start date: 2011-11-01, End date: 2017-10-31
Although the long term prognosis of patients suffering acute myocardial infarction (AMI) has improved since the introduction of reperfusion therapies and primary angioplasty, the 1 year mortality of patients with AMI and resultant left ventricular systolic dysfunction (LVSD) ...
Programme: FP7-HEALTH
Record Number: 101806
Last updated on: 2017-12-07
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List retrieved on: 2017-12-17
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