Community Research and Development Information Service - CORDIS

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Monitoring innate immunity in arthritis and mucosal inflammation
ID: 305266
Start date: 2013-02-01, End date: 2016-04-30
In chronic joint disease, only a subgroup of patients has classical autoantibodies, while the other variants are seronegative arthritis syndromes with a predominance of innate immune disturbances. These forms of joint diseases frequently show extra-articular manifestations of...
Programme: FP7-HEALTH
Record Number: 106695
Last updated on: 2017-12-07
Improving the organisation of maternal health service delivery, and optimising childbirth, by increasing vaginal birth after caesarean section (VBAC) through enhanced women-centred care
ID: 305208
Start date: 2012-09-01, End date: 2017-02-28
Optimal, healthy pregnancy followed by normal birth is the ideal. Caesarean section (CS) doubles the risk of mortality and morbidity (hysterectomy, blood transfusion), and increases the risk of postnatal infection by 5, compared with vaginal birth (WHO Global Survey on Matern...
Programme: FP7-HEALTH
Record Number: 105309
Last updated on: 2017-12-07
Supporting Low-cost Intervention For disEase control
ID: 305292
Start date: 2013-05-01, End date: 2017-04-30
In developing countries, most of the 11 million deaths per year of children under the age five years occur in areas where adequate medical care is not available. In Malawi the under-five mortality rate is 133 per 1,000 live births. First-level health facilities - the closest ...
Programme: FP7-HEALTH
Record Number: 106966
Last updated on: 2017-11-20
Translational Adolescent and Childhood Therapeutic Interventions in Compulsive Syndromes
ID: 278948
Start date: 2012-01-01, End date: 2018-06-30
Compulsivity is characterized by a repetitive, irresistible urge to perform a behavior, the experience of loss of voluntary control over this intense urge, the diminished ability to delay or inhibit thoughts or behaviors, and the tendency to perform repetitive acts in a habit...
Programme: FP7-HEALTH
Record Number: 101848
Last updated on: 2017-11-20
A Phase Ib/II study of MEK1/2 inhibitor PD-0325901 or MEK-162 with cMET inhibitor PF-02341066 in RASMT and RASWT (with aberrant c-MET) Colorectal Cancer Patients
ID: 602901
Start date: 2013-12-01, End date: 2020-11-30
Colorectal cancer (CRC) is the 3rd most common cancer in Europe, and with approximately 200,000 deaths per year, it remains the 2nd most common cause of cancer death. More than half of all CRC patients develop distant metastases and have 5-year overall survival (OS) of less t...
Programme: FP7-HEALTH
Record Number: 110280
Last updated on: 2017-11-20
Development and clinical trials of a new Software ENgine for the Assessment & Optimization of drug and non-drug Therapy in Older peRsons
ID: 305930
Start date: 2012-10-01, End date: 2018-06-30
The European population of older people with multiple chronic diseases (multimorbidity) is increasing steadily in tandem with the rising population of people aged ≥ 65 years. Older multimorbid people are at high risk of polypharmacy (PP), inappropriate prescribing (IP), adver...
Programme: FP7-HEALTH
Record Number: 105397
Last updated on: 2017-09-24
Identifying best practices for care-dependent elderly by Benchmarking Costs and outcomes of community care
ID: 305912
Start date: 2013-01-01, End date: 2016-12-31
Problem: The need for cost effective health systems in Europe is imperative in the context of an increasing demand for health care by growing numbers of elderly people and a shrinking working force. Many health care systems are changing and looking for mechanisms to ensure,...
Programme: FP7-HEALTH
Record Number: 106350
Last updated on: 2017-09-10
Mechanisms of prevention of type 2 diabetes by lifestyle intervention in subjects with pre-diabetes or at high-risk for progression
ID: 279228
Start date: 2012-01-01, End date: 2015-12-31
Type 2 diabetes (T2DM) is preventable by sustained changes in diet and physical exercise. Despite this, modern societies are already approaching 10% population prevalence of diabetes, and another 15% with pre-diabetes. The costs of T2DM are huge, approaching 10% of all health...
Programme: FP7-HEALTH
Record Number: 101811
Last updated on: 2017-09-10
Epilepsy Pharmacogenomics: delivering biomarkers for clinical use
ID: 279062
Start date: 2011-11-01, End date: 2015-10-31
The purpose of the project is to identify genome-based biomarkers for use in clinical practice to individualise treatment of epilepsy, and stratify patients for clinical trials, aiming to avoid chronicity, prevent relapse and reduce adverse drug reactions (ADRs). The need for...
Programme: FP7-HEALTH
Record Number: 101997
Last updated on: 2017-09-10
Fast Automated Multiplex Analysis of Neonatal Sepsis Markers on a Centrifugal Microfluidic Platform
ID: 258759
Start date: 2011-01-01, End date: 2014-06-30
The global frequency of neonatal sepsis is 1-21 newborns per 1000 live births with mortality rates as high as 35-70%, amounting to 100,000s of annual cases. The consortium has identified a real and pressing need for increasing diagnostic efficacy in a setting that imposes a d...
Programme: FP7-HEALTH
Record Number: 97617
Last updated on: 2017-09-10
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List retrieved on: 2017-12-17
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