Community Research and Development Information Service - CORDIS

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The NGF system and its interplay with endocannabinoid signalling, from peripheral sensory terminals to the brain: new targets for the development of next generation drugs for neuropathic pain
ID: 603191
Start date: 2014-04-01, End date: 2017-12-31
So far, there are no effective treatments for neuropathic pain (NP), and current treatments suffer from serious unwanted side effects. The NGF ligand-receptor system has recently emerged as a novel target for NP of great therapeutic potential, a master regulator, controlling ...
Programme: FP7-HEALTH
Record Number: 185456
Last updated on: 2017-10-06
Mechanisms and Treatment of Migraine and its Chronification
ID: 602633
Start date: 2014-02-01, End date: 2017-01-31
Migraine is a common brain disorder, typically characterised by recurring, incapacitating attacks of 1-3 days of severe headache, autonomic dysfunction, and sometimes aura symptoms. The disease affects 15% of all European citizens including children, ranks among the WHO top 1...
Programme: FP7-HEALTH
Record Number: 109470
Last updated on: 2017-10-06
European stem cell consortium for neural cell replacement, reprogramming and functional brain repair
ID: 602278
Start date: 2013-10-01, End date: 2017-09-30
Neurostemcellrepair aims at taking human stem cells through the final steps toward clinical application in cell replacement therapy for neurological disorders. PD will be taken as the prototypical disease because stem cell therapy is now close to clinical translation. Moreove...
Programme: FP7-HEALTH
Record Number: 110638
Last updated on: 2017-09-24
Human pluripotent stem cell differentiation, safety and preparation for therapeutic transplantation in Huntington’s disease
ID: 602245
Start date: 2013-10-01, End date: 2018-03-31
This project will tackle the huge complexity of taking stem cell therapies to clinical application for neurodegenerative disease by focusing on selective differentiation of a single neuronal phenotype (medium spiny striatal neuron: MSN) for a single well-defined disease (Hunt...
Programme: FP7-HEALTH
Record Number: 109572
Last updated on: 2017-09-24
Development and clinical trials of a new Software ENgine for the Assessment & Optimization of drug and non-drug Therapy in Older peRsons
ID: 305930
Start date: 2012-10-01, End date: 2018-06-30
The European population of older people with multiple chronic diseases (multimorbidity) is increasing steadily in tandem with the rising population of people aged ≥ 65 years. Older multimorbid people are at high risk of polypharmacy (PP), inappropriate prescribing (IP), adver...
Programme: FP7-HEALTH
Record Number: 105397
Last updated on: 2017-09-24
Stem-cell based therapy for kidney repair
ID: 305436
Start date: 2012-11-01, End date: 2017-10-31
Chronic kidney disease (CKD) affects 8% of the European population and ultimately results in renal failure due to progressive fibrosis. CDK carries a high mortality risk and the number of affected people rises, increasing the demand on renal replacement therapies while the nu...
Programme: FP7-HEALTH
Record Number: 105515
Last updated on: 2017-09-24
Towards clinical translation of new gene targeting technologies for correcting inherited mutations and empowering adoptive immunotherapy of cancer
ID: 601958
Start date: 2013-05-01, End date: 2016-10-31
Substantial evidence supports the therapeutic potential of ex vivo gene therapy based on Hematopoietic Stem Cell (HSC) or T lymphocytes to treat inherited diseases or cancer. Yet, the intrinsic limitations of current gene replacement approaches based on semi-randomly integrat...
Programme: FP7-HEALTH
Record Number: 108697
Last updated on: 2017-09-10
Identifying best practices for care-dependent elderly by Benchmarking Costs and outcomes of community care
ID: 305912
Start date: 2013-01-01, End date: 2016-12-31
Problem: The need for cost effective health systems in Europe is imperative in the context of an increasing demand for health care by growing numbers of elderly people and a shrinking working force. Many health care systems are changing and looking for mechanisms to ensure, m...
Programme: FP7-HEALTH
Record Number: 106350
Last updated on: 2017-09-10
Platform for sharing best practices for management of rare diseases
ID: 305690
Start date: 2013-01-01, End date: 2016-12-31
RARE-Bestpractices will develop a sustainable networking platform, supporting the collection of standardized and validated data and efficient exchange of knowledge and reliable information on rare diseases (RD). RD are characterized by low prevalence (EU – 5:10000 persons). T...
Programme: FP7-HEALTH
Record Number: 105806
Last updated on: 2017-09-10
Circulating Tumor Cells TheRapeutic APheresis: a novel biotechnology enabling personalized therapy for all cancer patients
ID: 305341
Start date: 2012-09-01, End date: 2016-08-31
"Chemotherapy is slowly being supplemented by a new generation of drugs that recognize specific targets in or on cancer cells and has proven to be more effective with markedly fewer side effects. During the course of the disease alternative oncogenic signaling pathways take o...
Programme: FP7-HEALTH
Record Number: 105310
Last updated on: 2017-09-10
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List retrieved on: 2017-10-20
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