Community Research and Development Information Service - CORDIS

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Novel antifungals to treat resistant organisms
ID: 601963
Start date: 2013-07-01, End date: 2016-06-30
Invasive fungal diseases are estimated to kill 1.5 million people each year. The incidence of mortality has risen significantly across the EU over the last 20 years due to an expansion of at risk patient populations. Given the obvious importance of these diseases it is perhap...
Programme: FP7-HEALTH
Record Number: 108714
Last updated on: 2017-09-10
Towards clinical translation of new gene targeting technologies for correcting inherited mutations and empowering adoptive immunotherapy of cancer
ID: 601958
Start date: 2013-05-01, End date: 2016-10-31
Substantial evidence supports the therapeutic potential of ex vivo gene therapy based on Hematopoietic Stem Cell (HSC) or T lymphocytes to treat inherited diseases or cancer. Yet, the intrinsic limitations of current gene replacement approaches based on semi-randomly integrat...
Programme: FP7-HEALTH
Record Number: 108697
Last updated on: 2017-09-10
Platform for sharing best practices for management of rare diseases
ID: 305690
Start date: 2013-01-01, End date: 2016-12-31
RARE-Bestpractices will develop a sustainable networking platform, supporting the collection of standardized and validated data and efficient exchange of knowledge and reliable information on rare diseases (RD). RD are characterized by low prevalence (EU – 5:10000 persons). T...
Programme: FP7-HEALTH
Record Number: 105806
Last updated on: 2017-09-10
Towards Early diagnosis and biomarker validation in Arthritis Management
ID: 305549
Start date: 2012-11-01, End date: 2016-10-31
An ideal intervention in a chronic inflammatory disease such as Rheumatoid Arthritis (RA) would be a preventive one. In order to develop preventive strategies and therapies two key developments need to occur: (1) Biomarkers need to be identified that can be used to predict an...
Programme: FP7-HEALTH
Record Number: 105516
Last updated on: 2017-09-10
Circulating Tumor Cells TheRapeutic APheresis: a novel biotechnology enabling personalized therapy for all cancer patients
ID: 305341
Start date: 2012-09-01, End date: 2016-08-31
"Chemotherapy is slowly being supplemented by a new generation of drugs that recognize specific targets in or on cancer cells and has proven to be more effective with markedly fewer side effects. During the course of the disease alternative oncogenic signaling pathways take o...
Programme: FP7-HEALTH
Record Number: 105310
Last updated on: 2017-09-10
Improving the organisation of maternal health service delivery, and optimising childbirth, by increasing vaginal birth after caesarean section (VBAC) through enhanced women-centred care
ID: 305208
Start date: 2012-09-01, End date: 2017-02-28
Optimal, healthy pregnancy followed by normal birth is the ideal. Caesarean section (CS) doubles the risk of mortality and morbidity (hysterectomy, blood transfusion), and increases the risk of postnatal infection by 5, compared with vaginal birth (WHO Global Survey on Matern...
Programme: FP7-HEALTH
Record Number: 105309
Last updated on: 2017-09-10
Generation of  a new class of antiretrovirals targeting HIV-cellular cofactors interactions
ID: 305137
Start date: 2012-10-01, End date: 2015-09-30
Highly active antiretroviral therapy is effective at controlling HIV-1 replication, however emergence and transmission of drug-resistant viruses is increasing, including viruses resistant to the newly developped integrase catalytic inhibitors. It is essential that new antiret...
Programme: FP7-HEALTH
Record Number: 105307
Last updated on: 2017-09-10
Mechanisms of prevention of type 2 diabetes by lifestyle intervention in subjects with pre-diabetes or at high-risk for progression
ID: 279228
Start date: 2012-01-01, End date: 2015-12-31
Type 2 diabetes (T2DM) is preventable by sustained changes in diet and physical exercise. Despite this, modern societies are already approaching 10% population prevalence of diabetes, and another 15% with pre-diabetes. The costs of T2DM are huge, approaching 10% of all health...
Programme: FP7-HEALTH
Record Number: 101811
Last updated on: 2017-09-10
Epilepsy Pharmacogenomics: delivering biomarkers for clinical use
ID: 279062
Start date: 2011-11-01, End date: 2015-10-31
The purpose of the project is to identify genome-based biomarkers for use in clinical practice to individualise treatment of epilepsy, and stratify patients for clinical trials, aiming to avoid chronicity, prevent relapse and reduce adverse drug reactions (ADRs). The need for...
Programme: FP7-HEALTH
Record Number: 101997
Last updated on: 2017-09-10
Virtual reality-Treadmill combined Intervention for enhancing Mobility and reducing falls in the Elderly
ID: 278169
Start date: 2012-01-01, End date: 2015-12-31
Falls are a major public health concern that directly affects millions of elderly Europeans, the healthcare system, and the adult children and caregivers of older people. The V-TIME approach combines cutting edge technology with emerging concepts from gerontology, neuroscienc...
Programme: FP7-HEALTH
Record Number: 101785
Last updated on: 2017-09-10
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List retrieved on: 2017-09-22
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