Community Research and Development Information Service - CORDIS

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A systems approach linking genotype and environment to phenotype: oxidative stress response mechanisms in fission yeast
ID: 223539
Start date: 2008-10-01, End date: 2012-03-31
Cellular protection against oxidative damage is relevant to ageing and numerous complex diseases. We plan to use fission yeast as a model organism to gain a systems-level understanding of the oxidative stress response and obtain insights into the interplay of variable genotyp...
Programme: FP7-HEALTH
Record Number: 88522
Last updated on: 2017-05-29
ID: 223077
Start date: 2008-10-01, End date: 2012-09-30
At present more than 5 million people in the EU suffer from dementia and other neurodegenerative diseases and that number will grow as the average age of the population continues to increase. The efficacy of current medicines is limited and new therapeutic targets are sorely ...
Programme: FP7-HEALTH
Record Number: 88499
Last updated on: 2017-05-29
Profiling the toxicity of new drugs: a non animal-based approach integrating toxicodynamics and biokinetics
ID: 202222
Start date: 2008-05-01, End date: 2013-10-31
The overall aim of Predict-IV is to develop strategies to improve the assessment of drug safety in the early stage of development and late discovery phase, by an intelligent combination of non animal-based test systems, cell biology, mechanistic toxicology and in-silico model...
Programme: FP7-HEALTH
Record Number: 86700
Last updated on: 2017-05-29
Rapid, robust & scaleable platform technology for fully automated reference laboratory grade Polymerase Chain Reaction (PCR) based diagnostics regardless of global setting
ID: 201569
Start date: 2008-07-01, End date: 2011-06-30
RANGER addresses the HEALTH-2007-2.3.3-4: Innovative point-of-care (POC) diagnostic tests for influenza call by providing a innovative solution to the immediate need for a rapid, robust, cost effective & user friendly POC diagnostic for influenza. We will develop the followin...
Programme: FP7-HEALTH
Record Number: 88189
Last updated on: 2017-05-29
“Improved methodology for data collection on accidents and disabilities – Integration of European Injury Statistics”
ID: 201524
Start date: 2008-05-01, End date: 2011-04-30
The implementation of a prevention-oriented injury surveillance in the EU is a major demand towards the Member States in the recent “EC Council Recommendations on the prevention of injury and the promotion of safety”. Needed in particular are valid and reliable indicators for...
Programme: FP7-HEALTH
Record Number: 88187
Last updated on: 2017-05-29
Genetic Analysis of the host-pathogen interaction in tuberculosis
ID: 201483
Start date: 2008-03-01, End date: 2011-08-31
We propose to extend an existing collection of DNA extracts from TB patients and their corresponding TB DNA to establish the world’s largest resource of extracts from a population of TB patients and 5000 ethnically matched healthly controls. The bank will comprise 5000 DNA ho...
Programme: FP7-HEALTH
Record Number: 88186
Last updated on: 2017-05-29
Unravelling the molecular basis of common complex human disorders using the dog as a model system
ID: 201370
Start date: 2008-01-01, End date: 2012-06-30
Despite major efforts, identifying susceptibility genes for common human diseases - cancer, cardiovascular, inflammatory and neurological disorders - is difficult due to the complexity of the underlying causes. The dog population is composed of ~ 400 purebred breeds; each one...
Programme: FP7-HEALTH
Record Number: 87971
Last updated on: 2017-05-29
Development of methodology for alternative testing strategies for the assessment of the toxicological profile of nanoparticles used in medical diagnostics
ID: 201335
Start date: 2008-04-01, End date: 2012-03-31
Nanoparticles (NP) have unique, potentially beneficial properties, but their possible impact on human health has not been adequately assessed. The main goal of this proposal is to develop alternative high-throughput testing strategies using in vitro and in silico methods to a...
Programme: FP7-HEALTH
Record Number: 86691
Last updated on: 2017-05-29
Increasing the PaRticipation of the ElDerly in Clinical Trials
ID: 201917
Start date: 2008-02-01, End date: 2010-07-31
AIM. To investigate the reasons for the exclusion of the elderly in clinical trials and to provide solutions for this problem. INTRODUCTION. Although the elderly account for high drug consumption, they are underrepresented in clinical trials. With an increasingly ageing Europ...
Programme: FP7-HEALTH
Record Number: 86770
Last updated on: 2017-05-29
Hybrid Fluorescence Molecular Tomography and X-ray Computed Tomography system and method
ID: 201792
Start date: 2008-03-01, End date: 2012-08-31
This proposal offers to combine X-ray CT (XCT) and Fluorescence Molecular Tomography (FMT) into a hybrid, quantitative system and method. The project builds on state-of the-art knowledge that only recently became available in different European states as represented by the pa...
Programme: FP7-HEALTH
Record Number: 86695
Last updated on: 2017-05-29
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List retrieved on: 2017-05-30
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