Community Research and Development Information Service - CORDIS

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Development of very promising humanized therapeutic mAbs efficiently neutralizing a novel immunosuppressive pathway involved in a wide range of cancers
ID: 602200
Start date: 2013-09-01, End date: 2018-02-28
Studies have demonstrated the importance of CD73 in the spread of cancer. Overexpressed in numerous cancer types, this enzyme leads to the production of high amounts of extracellular Adenosine, creating an immunosuppressive microenvironment, and contributing to tumor prolifer...
Programme: FP7-HEALTH
Record Number: 110188
Last updated on: 2017-05-29
ID: 201865
Start date: 2008-03-01, End date: 2012-08-31
Osteoporosis is a common, age-related disease with a strong genetic component. With increasing age of the population, Europe and industrialised countries across the globe are facing a substantial increase in osteoporotic fractures, which account for considerable disease-burde...
Programme: FP7-HEALTH
Record Number: 86697
Last updated on: 2017-05-29
Systems Biology of T-cell Activation in Health and Disease
ID: 201106
Start date: 2008-04-01, End date: 2013-09-30
T-cell activation, whether induced by pathogens or auto-antigens, is a complex process relying on multiple layers of tightly controlled intracellular signalling modules that form an intricate network. Defects in this network can cause severe and chronic disorders such as auto...
Programme: FP7-HEALTH
Record Number: 88091
Last updated on: 2017-05-29
ToxBank – Supporting Integrated Data Analysis and Servicing of Alternative Testing Methods in Toxicology
ID: 267042
Start date: 2011-01-01, End date: 2015-12-31
ToxBank establishes a dedicated web-based warehouse for toxicity data management and modelling, a ‘gold standards’ compound database and repository of selected test compounds, and a reference resource for cells, cell lines and tissues of relevance for in vitro systemic toxici...
Programme: FP7-HEALTH
Record Number: 97715
Last updated on: 2017-05-26
African Programme for Advanced  Research Epidemiology Training
ID: 265411
Start date: 2011-04-01, End date: 2014-12-31
The APARET fellowship programme will catalyse independent research activities of graduates of Field Epidemiology Training Programmes (FETP) and Field Epidemiology Laboratory Training programmes (FELTP) in Africa. APARET fellows will be employed as research associates by Afric...
Programme: FP7-HEALTH
Record Number: 98539
Last updated on: 2017-05-26
EUCOMM: Tools for Functional Annotation of the Mouse Genome
ID: 261492
Start date: 2010-10-01, End date: 2015-09-30
The EUCOMMTOOLS Collaborative Project responds to the topic ‘HEALTH.2010.2.1.1-1: Large-scale efforts in mouse functional genomics to determine the functions of genes and their involvement in disease.’ EUCOMMTOOLS will provide, in a systematic high-throughput way, genetic too...
Programme: FP7-HEALTH
Record Number: 96691
Last updated on: 2017-05-26
Infectious triggers of chronic autoimmunity
ID: 261382
Start date: 2010-11-01, End date: 2015-04-30
This proposal builds on existing expertise and collaborations of a multidisciplinary Consortium of basic scientists and clinical investigators each of whom has made a substantial individual contribution to understanding the links between infection and autoimmunity. The aim of...
Programme: FP7-HEALTH
Record Number: 96921
Last updated on: 2017-05-26
Open Collaborative Model for Tuberculosis Lead Optimisation
ID: 261378
Start date: 2011-01-01, End date: 2015-06-30
"Early stage Drug Discovery efforts over the last 5 years have resulted in the identification of a number of promising lead compounds in the fight against TB. These leads need to be further progressed and optimised into candidates for pre-clinical development through the Drug...
Programme: FP7-HEALTH
Record Number: 96802
Last updated on: 2017-05-26
International Human Microbiome Standards
ID: 261376
Start date: 2011-02-01, End date: 2015-01-31
A detailed understanding of human biology will require characterisation of the human-associated microorganisms, the human microbiome, and of the roles these microbes play in health and disease. Large projects in Europe, the United States, China and Canada target these objecti...
Programme: FP7-HEALTH
Record Number: 97703
Last updated on: 2017-05-26
International Research on Quality in Healthcare
ID: 261369
Start date: 2010-12-01, End date: 2014-04-30
International Research Project on Financing Quality in Healthcare InterQuality gathers the interest for financing systems' effect on quality of healthcare of researchers from seven EU countries and US. The study, based on administrative and survey data, is designed for 36 mon...
Programme: FP7-HEALTH
Record Number: 97172
Last updated on: 2017-05-26
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List retrieved on: 2017-05-30
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