Community Research and Development Information Service - CORDIS

Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Results 41 - 50 of 1008
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Anti-tick Vaccines to Prevent Tick-borne Diseases in Europe
ID: 602272
Start date: 2013-12-01, End date: 2018-11-30
Background Ixodes ricinus transmits bacterial, protozoal and viral pathogens that cause Lyme borreliosis, babesiosis and tick-borne encephalitis respectively and exceedingly affect Central and Eastern Europe (CEE). During feeding, ticks introduce salivary proteins in the skin...
Programme: FP7-HEALTH
Record Number: 109340
Last updated on: 2016-03-31
The development of a novel therapeutic vaccine for the selective treatment of the autoimmune disorder, Graves’ disease
ID: 602779
Start date: 2013-12-01, End date: 2017-11-30
This aim of the DAVIAD proposal is to develop a therapeutic vaccine for Graves’ disease (GD) that has a better safety and efficacy profile than current treatments. There is a high level of unmet need in the treatment of Graves’ disease especially in patients with Graves orbit...
Programme: FP7-HEALTH
Record Number: 110669
Last updated on: 2017-02-21
Disarming the intravascular innate immune response to improve treatment modalities for chronic kidney disease
ID: 602699
Start date: 2013-12-01, End date: 2017-11-30
Chronic kidney disease is world wide a major cause of end-stage renal disease (ESRD). 800.000 patients in Europe and in the US, respectively, require long-term treatment initially with peritoneal dialysis, followed by hemodialysis and kidney transplantation. Each ESRD patient...
Programme: FP7-HEALTH
Record Number: 110780
Last updated on: 2017-04-24
A Phase Ib/II study of MEK1/2 inhibitor PD-0325901 or MEK-162 with cMET inhibitor PF-02341066 in RASMT and RASWT (with aberrant c-MET) Colorectal Cancer Patients
ID: 602901
Start date: 2013-12-01, End date: 2020-11-30
Colorectal cancer (CRC) is the 3rd most common cancer in Europe, and with approximately 200,000 deaths per year, it remains the 2nd most common cause of cancer death. More than half of all CRC patients develop distant metastases and have 5-year overall survival (OS) of less t...
Programme: FP7-HEALTH
Record Number: 110280
Last updated on: 2016-11-14
Clonidine for Sedation of Paediatric Patients in the  Intensive Care Unit
ID: 602453
Start date: 2013-12-01, End date: 2018-11-30
The majority of critically ill children admitted to Paediatric Intensive Care Units (PICU) will require sedation and analgesia which is commonly achieved with a combination of an benzodiazepine and an opioid. However, these agents have a significant side-effect profile, inclu...
Programme: FP7-HEALTH
Record Number: 109466
Last updated on: 2017-03-22
Human stem cell applications for the treatment of hearing loss
ID: 603029
Start date: 2013-11-01, End date: 2017-10-31
Hearing impairment is the most frequent human sensory deficit and is mainly caused by the irreversible loss of neurosensory cells in the cochlea. The lack of human otic cell models represents a significant roadblock that has hampered the development of drug-based or cell-base...
Programme: FP7-HEALTH
Record Number: 110640
Last updated on: 2016-09-12
Taking imaging into the therapeutic domain: Self-regulation of brain systems for mental disorders
ID: 602186
Start date: 2013-11-01, End date: 2018-10-31
Our proposal is based on the idea that real-time functional neuroimaging can be used to train patients to regulate their own brain activity via neurofeedback training and thus modulate the brain networks of mental disorder, restore function, improve symptoms and promote resil...
Programme: FP7-HEALTH
Record Number: 109338
Last updated on: 2017-06-21
Long-term, prospective study evaluating clinical and molecular biomarkers of epileptogenesis in a genetic  model of epilepsy – tuberous sclerosis complex
ID: 602391
Start date: 2013-11-01, End date: 2018-10-31
Despite a great progress in the management of epilepsy, still one third of patients is refractory to available medications. The incidence of epilepsy is highest in infancy and 50% of children experience epilepsy-related comorbidities, such as developmental delay and autism. T...
Programme: FP7-HEALTH
Record Number: 110144
Last updated on: 2015-10-23
Advanced Studies towards Knowledge on Lyssavirus Encephalitis
Pathogenesis Improving Options for Survival
ID: 602825
Start date: 2013-11-01, End date: 2016-10-31
The overall aim of ASKLEPIOS is to unravel and increase our understanding of the mechanisms that govern pathogenesis of rabies virus (RABV) infection, in pursuit of the rational identification of novel therapeutic leads for rabies encephalitis. Several studies have been condu...
Programme: FP7-HEALTH
Record Number: 109348
Last updated on: 2017-02-21
Clinical Studies on a Multivalent Vaccine for Human Visceral Leishmaniasis
ID: 603181
Start date: 2013-11-01, End date: 2018-10-31
The World Health Organisation in its report on Neglected Tropical Diseases has stated that there is overwhelming evidence to show that the burden caused by many of the 17 diseases that affect more than 1billion people worldwide can be effectively controlled and, in many cases...
Programme: FP7-HEALTH
Record Number: 110417
Last updated on: 2017-06-05
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List retrieved on: 2017-06-23