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Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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FP7-IDEAS-ERC (1551)


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Results 1 - 10 of 1551
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The histone H3.3 variant in brain cancer pathogenesis
ID: 616744
Start date: 2014-05-01, End date: 2019-04-30
Epigenetic reprogramming is a hallmark of brain cancer. Remarkably, driver mutations of the histone H3.3 variant and its loading machinery have been recently found in paediatric glioblastoma multiforme (GBM), a devastating neoplasm originating from transformed neural precurso...
Programme: FP7-IDEAS-ERC
Record Number: 185637
Last updated on: 2017-07-16
Downhill Folding Protein Modules as Conformational Rheostats: Roles in Molecular Biology and Applications as Biosensors
ID: 323059
Start date: 2013-05-01, End date: 2018-04-30
Protein folding and function is a perfect arena towards growing the grassroots of quantitative and synthetic biology. This is so because all cellular processes controlled by proteins can ultimately be traced back to physico-chemical properties encoded in their aminoacid seque...
Programme: FP7-IDEAS-ERC
Record Number: 108432
Last updated on: 2017-07-16
Receptors, Channels and Transporters:
Development and Application of Novel Technologies for Structure Determination
ID: 339995
Start date: 2014-02-01, End date: 2019-01-31
Structure determination of G protein-coupled receptors (GPCRs) has been exceedingly successful over the last 5 years due to the development of complimentary generic methodologies that will now allow the structure determination of virtually any GPCR. However, these technologie...
Programme: FP7-IDEAS-ERC
Record Number: 111591
Last updated on: 2017-07-12
Quantitative network-level analysis of stochastic cell fate decisions
ID: 338200
Start date: 2013-10-01, End date: 2018-09-30
In a developing embryo, each cell has to assume the correct cell fate to yield a viable adult organism. It has become clear that the signaling networks that control development are heavily influenced by molecular noise, i.e. stochastic fluctuations on the molecular level. Int...
Programme: FP7-IDEAS-ERC
Record Number: 110391
Last updated on: 2017-07-12
Structural studies of human picornaviruses
[PROJECT] PICOSTRUCTURE - Structural studies of human picornaviruses
ID: 335855
Start date: 2014-03-01, End date: 2019-02-28
Many picornaviruses are human pathogens that cause diseases varying in symptoms from common cold to life-threatening encephalitis. Currently there are no anti-picornavirus drugs approved for human use. We propose to study molecular structures of picornaviruses and their life ...
Programme: FP7-IDEAS-ERC
Record Number: 110956
Last updated on: 2017-07-12
Nationwide prospective study on community-acquired bacterial meningitis: from genetics to therapy
ID: 281156
Start date: 2012-02-01, End date: 2017-01-31
Meningitis is an inflammation of the membranes covering the brain and spinal cord (the meninges). Each year 35,000 European patients suffer from bacterial meningitis, resulting in 7000 deaths and leaving 7000 disabled. Streptococcus pneumoniae and Neisseria meningitidis are t...
Programme: FP7-IDEAS-ERC
Record Number: 102320
Last updated on: 2017-07-12
Stabilizing the exposure of neutralization epitopes on HIV-1 envelope glycoprotein trimer vaccines
ID: 280829
Start date: 2012-01-01, End date: 2016-12-31
The impact of HIV/AIDS on world healthcare is tremendous, particularly in the Third World. To curtail the HIV epidemic a cheap and effective vaccine is urgently needed, but despite massive research efforts no vaccine is available yet. Although most vaccines work by inducing n...
Programme: FP7-IDEAS-ERC
Record Number: 102000
Last updated on: 2017-07-12
Dynamic signalling networks in Diabetic Nephropathy (DN)
– New avenues to a personalized therapy.-
ID: 616891
Start date: 2014-06-01, End date: 2019-05-31
Dynamic signalling networks in Diabetic Nephropathy (DN) – New avenues to a personalized therapy.- We have developed an exquisite experimental platform that facilitates the systematic unravelling of the signalling networks leading to (1) the initiation, (2) the progression an...
Programme: FP7-IDEAS-ERC
Record Number: 185642
Last updated on: 2017-07-02
Dynamics and Homeostasis of Germinal Zones in the Adult Vertebrate Brain
ID: 322936
Start date: 2013-09-01, End date: 2019-08-31
Neural stem cells (NSCs) are self-renewing and multipotent progenitors generating neurons and glia in the adult vertebrate brain. The success of NSC maintenance and mobilization varies widely among species, brain territories, pathological conditions and individual environment...
Programme: FP7-IDEAS-ERC
Record Number: 109101
Last updated on: 2017-07-02
The Molecular Communication Mechanism of Motor Neuron Survival and Synapse Maintenance
ID: 309377
Start date: 2013-02-01, End date: 2019-01-31
In order to survive and maintain normal function, the cell depends on a dynamic system of spatial specificity and fidelity of signaling pathways that can respond to both internal and external changes over space and time. This cell-cell communication is mediated by ligand-rece...
Programme: FP7-IDEAS-ERC
Record Number: 106160
Last updated on: 2017-07-02
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List retrieved on: 2017-07-25
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