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Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Results 1 - 10 of 1555
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New chemical biology for tailoring novel therapeutics
ID: 339367
Start date: 2014-03-01, End date: 2019-02-28
Most of our drugs derive from natural products, many more natural products possess biological activity but our inability to synthesise novel analogues hampers our ability to use them either as tools or medicines. Cyclic peptides are common structural motifs in natural product...
Programme: FP7-IDEAS-ERC
Record Number: 111208
Last updated on: 2017-12-11
Functional protein dynamics studied 
by solution- and solid-state NMR spectroscopy
ID: 311318
Start date: 2013-04-01, End date: 2019-01-31
Proteins are highly flexible objects that perform their functions by sampling a wide range of conformations. The characterization of such motions is, therefore, crucial to establish the link between protein structure and function. In this project we will use advanced nuclear ...
Programme: FP7-IDEAS-ERC
Record Number: 107661
Last updated on: 2017-12-11
Genetics and cell biology of K2P channels
ID: 337702
Start date: 2013-10-01, End date: 2019-09-30
Two-pore domain potassium channels (K2P) maintain the resting membrane potential of animal cells and therefore play a central role in the control of cellular excitability. In the vertebrate nervous system, various neuromodulators promote K2P closure, which depolarizes neurons...
Programme: FP7-IDEAS-ERC
Record Number: 110294
Last updated on: 2017-12-07
Engineering an artificial immune system with functional components assembled from prokaryotic parts and modules
ID: 322797
Start date: 2013-05-01, End date: 2019-04-30
The objective of this project is to overcome current limitations for antibody production that are inherent to the extant immune system of vertebrates. This will be done by creating an all-in-one artificial/synthetic counterpart based exclusively on prokaryotic parts, devices ...
Programme: FP7-IDEAS-ERC
Record Number: 107706
Last updated on: 2017-12-07
Regulation of Gene Expression by non-canonical poly(A) and poly(U) polymerases
ID: 309419
Start date: 2013-02-01, End date: 2019-01-31
In eukaryotes, almost all RNA molecules are processed at their 3’ ends and most mRNAs are polyadenylated in the nucleus by canonical poly(A) polymerases (PAPs). Recently, several new non-canonical poly(A) (ncPAPs) and poly(U) polymerases (PUPs) have been discovered that have ...
Programme: FP7-IDEAS-ERC
Record Number: 106869
Last updated on: 2017-12-07
NANOSCALE ANALYSIS OF PROTEIN ISLANDS ON LYMPHOCYTES
ID: 322972
Start date: 2013-05-01, End date: 2018-12-31
To detect foreign invaders and to communicate with other cells of the immune system, B lymphocytes carry a multitude of receptor proteins on their surface. In the past, it was thought that most of these receptors are randomly distributed on the cell surface and only become or...
Programme: FP7-IDEAS-ERC
Record Number: 107067
Last updated on: 2017-12-04
Learning to read the code of large neural populations
ID: 311238
Start date: 2013-01-01, End date: 2018-10-31
Information is represented and transmitted in the brain by the joint activity of large groups of neurons. Understanding how information is “written” in these population patterns, and how it is read and processed, is a fundamental question in neuroscience. Yet, because of the ...
Programme: FP7-IDEAS-ERC
Record Number: 106484
Last updated on: 2017-12-04
Towards a mechanistic understanding of mRNA localization
ID: 310957
Start date: 2013-01-01, End date: 2018-12-31
The localization of mRNAs has been increasingly recognized as a prominent mode of regulation of gene expression in eukaryotes. Localized RNAs can have crucial roles during animal development, in the maintenance of cell polarity and in nervous system function. Studies of RNA l...
Programme: FP7-IDEAS-ERC
Record Number: 105717
Last updated on: 2017-12-04
ABYSS - Assessment of bacterial life and matter cycling in deep-sea surface sediments
ID: 294757
Start date: 2012-06-01, End date: 2018-05-31
The deep-sea floor hosts a distinct microbial biome covering 67% of the Earth’s surface, characterized by cold temperatures, permanent darkness, high pressure and food limitation. The surface sediments are dominated by bacteria, with on average a billion cells per ml. Benthic...
Programme: FP7-IDEAS-ERC
Record Number: 103849
Last updated on: 2017-12-04
Quantitative Molecular Map of the Neuronal Surface
ID: 293681
Start date: 2012-02-01, End date: 2017-01-31
The most fundamental roles of nerve cells are the detection of chemical neurotransmitters to generate synaptic potentials; the summation of these potentials to create their output signals; and the consequent release of their own neurotransmitter molecules. All of these functi...
Programme: FP7-IDEAS-ERC
Record Number: 102234
Last updated on: 2017-12-04
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List retrieved on: 2017-12-14
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