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Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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FP7-IDEAS-ERC (163)

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Results 1 - 10 of 163
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Stabilizing the exposure of neutralization epitopes on HIV-1 envelope glycoprotein trimer vaccines
ID: 280829
Start date: 2012-01-01, End date: 2016-12-31
The impact of HIV/AIDS on world healthcare is tremendous, particularly in the Third World. To curtail the HIV epidemic a cheap and effective vaccine is urgently needed, but despite massive research efforts no vaccine is available yet. Although most vaccines work by inducing n...
Programme: FP7-IDEAS-ERC
Record Number: 102000
Last updated on: 2017-07-12
Improved Cryopreservation using Ice Binding Proteins
ID: 281595
Start date: 2011-11-01, End date: 2016-10-31
Several organisms have evolved specialized ice binding proteins (IBPs) that prevent their body fluids from freezing (antifreeze proteins, AFPs), inhibit recrystallization of ice in frozen tissues, or initiate freezing at moderate supercooling temperatures (ice nucleating prot...
Programme: FP7-IDEAS-ERC
Record Number: 101006
Last updated on: 2017-07-02
THE ENDOCYTIC AND CYTOSKELETAL MATRIX IN THE PLASTICITY OF TUMOR CELL INVASION AND MIGRATION
ID: 268836
Start date: 2011-08-01, End date: 2016-07-31
"Tumor cells can adopt different modes of cell motility. The ability to switch between diverse modes of migration enables tumors to adapt to micro-environmental conditions and to metastasize. The critical pathways and cellular processes underlying the plasticity of tumor cell...
Programme: FP7-IDEAS-ERC
Record Number: 99566
Last updated on: 2017-06-26
SUMOrice: Exploiting an emerging protein modification system, SUMOylation to boost rice yield during drought and salt stress
ID: 310235
Start date: 2013-04-01, End date: 2019-03-31
"To feed 9 billion people by 2050 is an unprecedented challenge. Rice is the food source for the majority of the world's population but also a model for cereals. Drought and related high salinity during essential periods of plant growth affects nearly all crops including the ...
Programme: FP7-IDEAS-ERC
Record Number: 107495
Last updated on: 2017-06-21
Reverse engineering the vertebrate molecular machinery for magnetic biomineralisation
ID: 311552
Start date: 2013-01-01, End date: 2017-12-31
In order to understand distributed biological networks and invent effective molecular therapies, we need to be able to image and control molecular processes across entire live organisms. Although an arsenal of genetically encoded fluorescent sensors and light-activated protei...
Programme: FP7-IDEAS-ERC
Record Number: 106439
Last updated on: 2017-06-12
General and targeted approaches to unravel the molecular causes of type 2 diabetes
ID: 269045
Start date: 2011-05-01, End date: 2016-04-30
Type 2 diabetes (T2D) affects worldwide at present about 250 million patients and an estimated 380 million in 2025. This epidemic has been ascribed to a collision between genes and an affluent society. Genetics of T2D has during recent years identified > 30 variants increasin...
Programme: FP7-IDEAS-ERC
Record Number: 98878
Last updated on: 2017-05-29
Metabolic consequences of mitochondrial dysfunction
ID: 268955
Start date: 2011-06-01, End date: 2016-05-31
This proposal aims to clarify mitochondrial contribution to obesity and thinness, using carefully characterized mitochondrial disease and obese patient materials, and genetically modified disease models. Manifestations of mitochondrial respiratory chain (RC) defects range fro...
Programme: FP7-IDEAS-ERC
Record Number: 99290
Last updated on: 2017-05-29
APL a model for oncogene-targeted leukemia cure
ID: 268729
Start date: 2011-07-01, End date: 2017-06-30
Acute promyelocytic leukaemia, APL, is probably one of the best-understood malignancies and the only one where highly efficient oncogene-targeted therapies (retinoic acid and arsenic) actually cure the disease. Our recent studies have addressed the molecular basis for transfo...
Programme: FP7-IDEAS-ERC
Record Number: 99545
Last updated on: 2017-05-29
KRAB/KAP1-mediated gene regulation in mammalian physiology and human diseases
ID: 268721
Start date: 2011-04-01, End date: 2016-03-31
This project aims at exploring the roles or KRAB/KAP1-mediated gene regulation in mammalian physiology and the possible impact of its dysfunctions on human health. The proper control of gene expression is paramount to all biological events, and is orchestrated through a sophi...
Programme: FP7-IDEAS-ERC
Record Number: 98546
Last updated on: 2017-05-29
From gene to biomineral: Biosynthesis and application of sponge biosilica
ID: 268476
Start date: 2011-06-01, End date: 2017-05-31
During the last decade, the principles of biomineralization have increasingly attracted multidisciplinary scientific attention, not only because they touch the interface between the organic/inorganic world but also because they offer fascinating bioinspired solutions to notor...
Programme: FP7-IDEAS-ERC
Record Number: 98358
Last updated on: 2017-05-29
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List retrieved on: 2017-07-24
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