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Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Results 1 - 10 of 163
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Single Molecule Enzymology with ClyA Nanopores
ID: 260884
Start date: 2010-11-01, End date: 2016-10-31
Single molecules based techniques provide the ultimate toolkit to study complex biological systems. In single-molecule approaches, molecules do not need to be synchronised as in ensemble studies, and rare and/or transient species along a reaction pathway as well as heterogene...
Programme: FP7-IDEAS-ERC
Record Number: 95813
Last updated on: 2017-04-10
An in vivo imaging approach to understand pancreatic beta-cell signal-transduction
ID: 338936
Start date: 2014-03-01, End date: 2019-02-28
The challenge in cell physiology/pathology today is to translate in vitro findings to the living organism. We have developed a unique approach where signal-transduction can be investigated in vivo non-invasively, longitudinally at single cell resolution, using the anterior ch...
Programme: FP7-IDEAS-ERC
Record Number: 185396
Last updated on: 2017-04-03
Targeting RAS oncogene addiction
[PROJECT] RASTARGET - Targeting RAS oncogene addiction
ID: 323145
Start date: 2013-05-01, End date: 2018-04-30
Lung cancer is the most common type of malignant tumour worldwide and the leading cause of cancer-related death (335,000 deaths per year in Europe). The KRAS oncogene is frequently activated by point mutation in human lung cancer and mutations in the RAS family oncogenes are ...
Programme: FP7-IDEAS-ERC
Record Number: 108040
Last updated on: 2017-03-22
FUTUREROOTS: Redesigning root architecture for improved crop performance
ID: 294729
Start date: 2012-08-01, End date: 2017-07-31
Food security is a pressing global issue. Crop production has to double by 2050 to keep pace with global population growth increasing to 9 billion. This target is challenging given the impact of climate change on water availability and the drive to reduce fertilizer inputs to...
Programme: FP7-IDEAS-ERC
Record Number: 103475
Last updated on: 2017-03-22
METABOLIC BASIS OF NEURODEGENERATIVE DISEASE
ID: 335692
Start date: 2014-02-01, End date: 2019-01-31
Alzheimer disease (AD) is the most common form of age-related dementia affecting millions of patients worldwide. Disturbingly, disorders of lipid and glucose metabolism emerge as major risk factors for onset and progression of neurodegeneration in the human population. Thus, ...
Programme: FP7-IDEAS-ERC
Record Number: 111063
Last updated on: 2017-03-06
Designed Plant Breeding by Control of Meiotic Recombination
ID: 268520
Start date: 2011-09-01, End date: 2016-08-31
Agriculture depends on breeding. Breeders try to combining desirable and eliminating unfavourable traits of crop plants. Changes in genetic linkage are based on meiotic recombination. Although techniques for the transfer of single traits have been developed, resulting in gene...
Programme: FP7-IDEAS-ERC
Record Number: 99500
Last updated on: 2017-03-06
Customized Micro Total Analysis Systems to Study Human Phase I Metabolism
ID: 311705
Start date: 2013-05-01, End date: 2019-02-28
The goal of this project is to develop inexpensive, high-throughput technology to screen the thus far unexplored metabolic interactions between environmental and household chemicals and clinically relevant drugs. The main influential focus will be on human phase I metabolism ...
Programme: FP7-IDEAS-ERC
Record Number: 106984
Last updated on: 2017-02-27
Signal integration and rewiring during tumor development
ID: 294665
Start date: 2012-07-01, End date: 2017-12-31
Cell fate decisions rely on signaling pathways that integrate external signals to coordinate specific intracellular programs. One of these pathways leads to the activation of p38α MAPK, which plays key roles in cell responses to many types of stresses as well as chemotherapeu...
Programme: FP7-IDEAS-ERC
Record Number: 103689
Last updated on: 2017-02-27
Metabolic consequences of mitochondrial dysfunction
ID: 268955
Start date: 2011-06-01, End date: 2016-05-31
This proposal aims to clarify mitochondrial contribution to obesity and thinness, using carefully characterized mitochondrial disease and obese patient materials, and genetically modified disease models. Manifestations of mitochondrial respiratory chain (RC) defects range fro...
Programme: FP7-IDEAS-ERC
Record Number: 99290
Last updated on: 2017-01-30
An Integrated Network of  Glucose Sensing Cells in Glucose Homeostasis
ID: 268946
Start date: 2011-08-01, End date: 2016-07-31
Glucose sensing cells constantly monitor glucose absorption from food and variations in blood glycemic levels. They control the secretion of GLP-1, insulin and glucagon, and the activity of the autonomic nervous system. These hormonal and nervous signals coordinate glucose ut...
Programme: FP7-IDEAS-ERC
Record Number: 99624
Last updated on: 2017-01-30
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List retrieved on: 2017-04-27
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