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Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Genetic/epigenetic basis of ethnic differences in cancer predisposition
ID: 340588
Start date: 2014-02-01, End date: 2020-01-31
"Integration of large scale genetic and epigenetic analysis needs to be coupled with well defined biological hypotheses that can be experimentally tested. This project is aimed at developing a novel integrated approach to understand genetic and epigenetic predisposition to ca...
Programme: FP7-IDEAS-ERC
Record Number: 110855
Last updated on: 2017-11-20
Directed evolution of a synthetic episome based on hexitol nucleic acids (HNA)
ID: 336936
Start date: 2014-02-01, End date: 2019-01-31
A long term goal of synthetic biology is the assembly of a cell from its individual components. A genetic element based on synthetic nucleic acids capable of stable propagation, a synthetic episome, is the minimal genetic element required for the systematic development of all...
Programme: FP7-IDEAS-ERC
Record Number: 111023
Last updated on: 2017-11-20
Development and application of global lipidomic arrays to inflammatory vascular disease
ID: 339129
Start date: 2014-02-01, End date: 2019-01-31
How lipids are regulated on a global scale during vascular inflammation is not known. Thus, a major challenge exists to describe and catalog the total lipidome, in particular enabling the identification of new biologically active lipids, and description of changes. This is an...
Programme: FP7-IDEAS-ERC
Record Number: 111069
Last updated on: 2017-11-20
Light-driven Chemical Synthesis using Cytochrome P450s
ID: 323034
Start date: 2013-03-01, End date: 2019-02-28
The goal of this proposed research initiative is to engineer chloroplasts into production units for high value bio-active natural products. The first aim is to re-route the biosynthetic pathways for these compounds into the chloroplast and to boost compound formation by optim...
Programme: FP7-IDEAS-ERC
Record Number: 107068
Last updated on: 2017-11-20
Molecular determinants of aphid host range
ID: 310190
Start date: 2013-02-01, End date: 2018-10-31
Many aphid species are restricted to one or few host plants, while some aphids, many of which are of agricultural importance, can infest a wide range of plant species. An important observation is that aphids spend a considerable time on nonhost species, where they probe the l...
Programme: FP7-IDEAS-ERC
Record Number: 105786
Last updated on: 2017-11-20
Exploiting plants for the production of future generation recombinant pharmaceuticals
ID: 269110
Start date: 2011-08-01, End date: 2019-01-31
Biopharmaceutical proteins are typically produced in cultivated mammalian cells, a costly process with limited scalability. Thus products such as monoclonal antibodies are very expensive and often beyond the reach of the world’s poor. The problem is compounded by the fact tha...
Programme: FP7-IDEAS-ERC
Record Number: 99830
Last updated on: 2017-11-20
Symbiotic bacteria as a delivery system for Nanobodies that target the insect-parasite interplay
ID: 282312
Start date: 2011-11-01, End date: 2016-10-31
The tsetse fly (Glossina spp.) salivary gland is the final micro-environment where the Trypanosoma brucei parasites adhere and undergo a complex re-programming cycle resulting in an end stage that is re-programmed to continue its life cycle in a new mammalian host. The molecu...
Programme: FP7-IDEAS-ERC
Record Number: 101104
Last updated on: 2017-11-20
Silicon transport proteins in biological nanoscience and synthetic biology
ID: 282101
Start date: 2011-10-01, End date: 2016-09-30
This interdisciplinary proposal will investigate whether the activity of a unique family of membrane transport proteins can be harnessed to develop novel strategies for the bioinspired fabrication of nanoscale materials and provide new directions in synthetic biology. Silicon...
Programme: FP7-IDEAS-ERC
Record Number: 100129
Last updated on: 2017-11-20
Role of Liver Estrogen Receptor in female Energy Metabolism, Reproduction and Aging: What About Your Liver Sexual Functions?
ID: 322977
Start date: 2013-04-01, End date: 2019-03-31
In mammals, the liver is the peripheral integrator of nutrient availability and energetic needs of the entire organism. We recently demonstrated that dietary amino acids (AA) activate liver Estrogen Receptors (ER) and that, in case of food scarcity, the lowered circulating AA...
Programme: FP7-IDEAS-ERC
Record Number: 108039
Last updated on: 2017-11-20
Ion homeostasis and volume regulation of cells and organelles
ID: 294435
Start date: 2012-04-01, End date: 2017-03-31
The regulation of ion concentrations in the cytoplasm and in the lumen of intracellular vesicles provides suitable environments for biochemical reactions, gradients for signal transduction, and generates osmotic gradients for the regulation of the volume of cells and intracel...
Programme: FP7-IDEAS-ERC
Record Number: 102290
Last updated on: 2017-11-20
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List retrieved on: 2017-11-23
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