Community Research and Development Information Service - CORDIS

Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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The histone H3.3 variant in brain cancer pathogenesis
ID: 616744
Start date: 2014-05-01, End date: 2019-04-30
Epigenetic reprogramming is a hallmark of brain cancer. Remarkably, driver mutations of the histone H3.3 variant and its loading machinery have been recently found in paediatric glioblastoma multiforme (GBM), a devastating neoplasm originating from transformed neural precurso...
Programme: FP7-IDEAS-ERC
Record Number: 185637
Last updated on: 2017-07-16
Stabilizing the exposure of neutralization epitopes on HIV-1 envelope glycoprotein trimer vaccines
ID: 280829
Start date: 2012-01-01, End date: 2016-12-31
The impact of HIV/AIDS on world healthcare is tremendous, particularly in the Third World. To curtail the HIV epidemic a cheap and effective vaccine is urgently needed, but despite massive research efforts no vaccine is available yet. Although most vaccines work by inducing n...
Programme: FP7-IDEAS-ERC
Record Number: 102000
Last updated on: 2017-07-12
Dynamic signalling networks in Diabetic Nephropathy (DN)
– New avenues to a personalized therapy.-
ID: 616891
Start date: 2014-06-01, End date: 2019-05-31
Dynamic signalling networks in Diabetic Nephropathy (DN) – New avenues to a personalized therapy.- We have developed an exquisite experimental platform that facilitates the systematic unravelling of the signalling networks leading to (1) the initiation, (2) the progression an...
Programme: FP7-IDEAS-ERC
Record Number: 185642
Last updated on: 2017-07-02
Improved Cryopreservation using Ice Binding Proteins
ID: 281595
Start date: 2011-11-01, End date: 2016-10-31
Several organisms have evolved specialized ice binding proteins (IBPs) that prevent their body fluids from freezing (antifreeze proteins, AFPs), inhibit recrystallization of ice in frozen tissues, or initiate freezing at moderate supercooling temperatures (ice nucleating prot...
Programme: FP7-IDEAS-ERC
Record Number: 101006
Last updated on: 2017-07-02
ID: 268836
Start date: 2011-08-01, End date: 2016-07-31
"Tumor cells can adopt different modes of cell motility. The ability to switch between diverse modes of migration enables tumors to adapt to micro-environmental conditions and to metastasize. The critical pathways and cellular processes underlying the plasticity of tumor cell...
Programme: FP7-IDEAS-ERC
Record Number: 99566
Last updated on: 2017-06-26
ID: 268804
Start date: 2011-06-01, End date: 2016-05-31
This application promises to provide new treatment options for cancer and cardiovascular diseases that are the leading causes of morbidity and mortality in the western world. Current cardiovascular and cancer therapies are often insufficient, unsuccessful or not suitable for ...
Programme: FP7-IDEAS-ERC
Record Number: 99210
Last updated on: 2017-06-26
SUMOrice: Exploiting an emerging protein modification system, SUMOylation to boost rice yield during drought and salt stress
ID: 310235
Start date: 2013-04-01, End date: 2019-03-31
"To feed 9 billion people by 2050 is an unprecedented challenge. Rice is the food source for the majority of the world's population but also a model for cereals. Drought and related high salinity during essential periods of plant growth affects nearly all crops including the ...
Programme: FP7-IDEAS-ERC
Record Number: 107495
Last updated on: 2017-06-21
Size Matters in Numerical Cognition
ID: 295644
Start date: 2012-09-01, End date: 2018-08-31
Numerical cognition is essential to many aspects of life and arithmetic abilities predict academic achievements better than reading. Acquiring a solid sense of numbers and being able to mentally manipulate numbers are at the heart of this ability. In recent years research has...
Programme: FP7-IDEAS-ERC
Record Number: 104845
Last updated on: 2017-06-21
OsteoMotion: Analyzing the mechanisms and role of osteogenic cell movement in bone development and disease
ID: 282131
Start date: 2011-11-01, End date: 2016-10-31
Bone development and homeostasis must incontestably rely on a correct spatial positioning of osteoblasts to generate bone at appropriate sites. A failure of osteoblasts to reach the sites in need of bone formation may contribute to impaired fracture repair and osteoporosis. C...
Programme: FP7-IDEAS-ERC
Record Number: 100905
Last updated on: 2017-06-21
Reverse engineering the vertebrate molecular machinery for magnetic biomineralisation
ID: 311552
Start date: 2013-01-01, End date: 2017-12-31
In order to understand distributed biological networks and invent effective molecular therapies, we need to be able to image and control molecular processes across entire live organisms. Although an arsenal of genetically encoded fluorescent sensors and light-activated protei...
Programme: FP7-IDEAS-ERC
Record Number: 106439
Last updated on: 2017-06-12
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List retrieved on: 2017-07-25
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