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Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Results 1 - 10 of 558
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The Plant Immune System: a multidisciplinary approach to uncover how plants simultaneously deal with beneficial and parasitic organisms to maximize profits and protection
ID: 269072
Start date: 2011-03-01, End date: 2017-02-28
In nature, plants live in complex environments in which they are attacked by a multitude of pathogens and pests. In agriculture this leads to tremendous annual crop losses, representing a value of over 450 billion worldwide. Beneficial associations between plants and other or...
Programme: FP7-IDEAS-ERC
Record Number: 98059
Last updated on: 2017-05-26
Mimicking pathogens; an integrated nano-medicine approach to developing intelligent cancer vaccines
ID: 269019
Start date: 2011-11-01, End date: 2017-10-31
Tumour cells survive and grow because they are not effectively recognized by the immune system as ¿foreign¿ and are therefore not attacked and destroyed like most pathogens. We have already demonstrated the clinical value of dendritic cell (DC) vaccines that activate the immu...
Programme: FP7-IDEAS-ERC
Record Number: 100675
Last updated on: 2017-05-26
GEnetic NEtworks as a tool for anti-CAncer Drug Development
ID: 268815
Start date: 2011-03-01, End date: 2016-02-29
Although several therapies target cellular pathways, current small molecules drug discovery is based on identification of inhibitors to single proteins, without knowledge of whether they are the most advantageous target. The objective of this proposal is to develop a novel me...
Programme: FP7-IDEAS-ERC
Record Number: 98152
Last updated on: 2017-05-26
In vivo biology of the mononuclear phagocyte system. A molecular & functional approach
ID: 261299
Start date: 2010-11-01, End date: 2015-10-31
Leucocytes are hemopoietic cells involved in tissue homeostasis, inflammation, and the defence against infection. Recent efforts have focused on the innate immune system , responsible for the early defence against pathogens, at the cost of tissue inflammation and inflammatory...
Programme: FP7-IDEAS-ERC
Record Number: 96591
Last updated on: 2017-05-26
Revealing the mechanism of host membrane rupture by invasive pathogens and its role in triggering the immune response
ID: 261166
Start date: 2011-03-01, End date: 2016-08-31
Pathogens have been evolving with their hosts for millions of years adopting tailored strategies to propagate within the host body and evading the host immune response. It is crucial to understand the underlying strategies employed by pathogens on the cellular and molecular l...
Programme: FP7-IDEAS-ERC
Record Number: 98072
Last updated on: 2017-05-26
Single-Molecule BioAssays at Elevated Concentrations
ID: 261162
Start date: 2010-11-01, End date: 2016-10-31
In order to advance single-molecule fluorescence spectroscopy to the next level, handling and analysis of single molecules has to become broadly available. A further quantum leap is required to proceed to commercially successful applications such as drug screening and medical...
Programme: FP7-IDEAS-ERC
Record Number: 96689
Last updated on: 2017-05-26
Microbial translocation across host barriers
ID: 261157
Start date: 2010-11-01, End date: 2016-10-31
Infections remain the primary cause of mortality in humans. New infections are emerging, and resistance to antimicrobial drugs is widespread and expanding. There is thus an urgent need to develop novel therapeutic strategies based on rationally-designed drugs blocking the pat...
Programme: FP7-IDEAS-ERC
Record Number: 96590
Last updated on: 2017-05-26
Modeling congenital heart disease (CHD) in ISL1+ cardiovascular progenitors from patient-specific iPS cells
ID: 261053
Start date: 2011-03-01, End date: 2017-02-28
Tetralogy of Fallot (TOF) is the most common congenital heart disease (CHD) occurring 1 in 3000 births. Genetic studies have identified numerous genes that are responsible for inherited and sporadic forms of TOF, most of which encode key molecules that are part of regulatory ...
Programme: FP7-IDEAS-ERC
Record Number: 98145
Last updated on: 2017-05-26
Floral Integrating Networks at the Shoot Apical Meristem of Rice
ID: 260963
Start date: 2011-04-01, End date: 2016-03-31
Discriminating differences in day length is critical for many organisms to synchronize reproduction with the most favourable season of the year. Plants have evolved sophisticated time-keeping mechanisms that largely work in leaves, to measure the duration of the day. Upon per...
Programme: FP7-IDEAS-ERC
Record Number: 97818
Last updated on: 2017-05-26
Single Molecule Enzymology with ClyA Nanopores
ID: 260884
Start date: 2010-11-01, End date: 2016-10-31
Single molecules based techniques provide the ultimate toolkit to study complex biological systems. In single-molecule approaches, molecules do not need to be synchronised as in ensemble studies, and rare and/or transient species along a reaction pathway as well as heterogene...
Programme: FP7-IDEAS-ERC
Record Number: 95813
Last updated on: 2017-05-26
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List retrieved on: 2017-05-27
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