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Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Engineering an artificial immune system with functional components assembled from prokaryotic parts and modules
ID: 322797
Start date: 2013-05-01, End date: 2019-04-30
The objective of this project is to overcome current limitations for antibody production that are inherent to the extant immune system of vertebrates. This will be done by creating an all-in-one artificial/synthetic counterpart based exclusively on prokaryotic parts, devices ...
Programme: FP7-IDEAS-ERC
Record Number: 107706
Last updated on: 2017-12-07
Novel Tools for Early Childhood Predisposition to Obesity
ID: 293574
Start date: 2012-09-01, End date: 2018-08-31
An estimated 22 million children worldwide under age five are overweight. In these children, obesity is a primary indicator for development of type 2 diabetes and possibly cancer. I present a research program, SELECTionPREDISPOSED, to identify novel obesity-risk genes as tool...
Programme: FP7-IDEAS-ERC
Record Number: 103540
Last updated on: 2017-12-04
General and targeted approaches to unravel the molecular causes of type 2 diabetes
ID: 269045
Start date: 2011-05-01, End date: 2016-04-30
Type 2 diabetes (T2D) affects worldwide at present about 250 million patients and an estimated 380 million in 2025. This epidemic has been ascribed to a collision between genes and an affluent society. Genetics of T2D has during recent years identified > 30 variants increasin...
Programme: FP7-IDEAS-ERC
Record Number: 98878
Last updated on: 2017-12-04
Single-Molecule BioAssays at Elevated Concentrations
ID: 261162
Start date: 2010-11-01, End date: 2016-10-31
In order to advance single-molecule fluorescence spectroscopy to the next level, handling and analysis of single molecules has to become broadly available. A further quantum leap is required to proceed to commercially successful applications such as drug screening and medical...
Programme: FP7-IDEAS-ERC
Record Number: 96689
Last updated on: 2017-12-04
Development and plasticity of multisensory functions to study the principles of age dependent learning plasticity in humans
ID: 249425
Start date: 2010-12-01, End date: 2016-11-30
Proposal summary: The present project will investigate the main principles of development and neuroplasticity in humans in the domain of multisensory processes (the interplay between sensory systems). It will be tested how learning plasticity of the human brain changes from c...
Programme: FP7-IDEAS-ERC
Record Number: 96726
Last updated on: 2017-12-04
Genetic/epigenetic basis of ethnic differences in cancer predisposition
ID: 340588
Start date: 2014-02-01, End date: 2020-01-31
"Integration of large scale genetic and epigenetic analysis needs to be coupled with well defined biological hypotheses that can be experimentally tested. This project is aimed at developing a novel integrated approach to understand genetic and epigenetic predisposition to ca...
Programme: FP7-IDEAS-ERC
Record Number: 110855
Last updated on: 2017-11-20
Directed evolution of a synthetic episome based on hexitol nucleic acids (HNA)
ID: 336936
Start date: 2014-02-01, End date: 2019-01-31
A long term goal of synthetic biology is the assembly of a cell from its individual components. A genetic element based on synthetic nucleic acids capable of stable propagation, a synthetic episome, is the minimal genetic element required for the systematic development of all...
Programme: FP7-IDEAS-ERC
Record Number: 111023
Last updated on: 2017-11-20
Positioning the nucleus for cell migration and muscle fiber function
ID: 617676
Start date: 2014-07-01, End date: 2019-06-30
The cell nucleus is positioned at specific places within the cytoplasm and this position is important for different cellular, developmental and physiological processes. Nuclear positioning depends on connections between nuclear envelope proteins and the cytoskeleton. In migra...
Programme: FP7-IDEAS-ERC
Record Number: 189851
Last updated on: 2017-11-20
Intracellular antibody Immunity
ID: 281627
Start date: 2012-01-01, End date: 2016-12-31
Antibodies are a critical component of immune defence but they provide purely extracellular protection – once inside a cell, a pathogen is safe. This is the view of humoral immunity that has existed for over 100 years. However, recent work in my lab has led to the discovery o...
Programme: FP7-IDEAS-ERC
Record Number: 100264
Last updated on: 2017-11-20
Randomized controlled trial of metformin and dietary restriction to prevent age-related morbid events in people with  metabolic syndrome
ID: 322752
Start date: 2013-08-01, End date: 2019-07-31
Age–related chronic diseases (ArCD) are complex non-linear processes that depends on a large number of interconnected genetic and metabolic pathways which should be tackled with a many faceted preventive strategy. Calorie-dense diet and sedentary lifestyle are responsible of ...
Programme: FP7-IDEAS-ERC
Record Number: 108844
Last updated on: 2017-11-20
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List retrieved on: 2017-12-14
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